Simbrinza drops

About Simbrinza drops

Simbrinza drops Uses

• Open-angle glaucoma
• Raised pressure inside the eye (ocular hypertension)
• Protecting the optic nerve from pressure damage
• When one glaucoma drop is not enough

Drug Class

• Anti-glaucoma eye drop combination
• Carbonic anhydrase inhibitor plus alpha-2 agonist

What Experts Say

This drop combines two medicines that lower eye pressure in different ways. Brinzolamide reduces the amount of fluid the eye makes, while brimonidine both reduces fluid production and improves its drainage, giving stronger combined control.

Combining two agents in one bottle is convenient and helps when a single medicine has not brought eye pressure to target. Controlling pressure is key to preventing the optic nerve damage that causes glaucoma vision loss.

Pressing gently on the inner corner of the eye after instilling the drop reduces how much is absorbed into the body. Any marked drowsiness, eye allergy or unusual taste should be reported, and lenses removed before use.

Simbrinza drops formula

• Brinzolamide 1%
• Brimonidine Tartrate 0.2%

Available forms

• Drops

How to use Simbrinza drops?

• Shake the bottle well and instil one drop into the affected eye or eyes as prescribed.
• Usually used two to three times daily.
• Press gently on the inner corner of the eye for a minute after use.
• Remove contact lenses first and wait before reinserting.
• Use every day at the prescribed times to keep pressure controlled.

Drug Interactions

This combination can interact with medicines affecting the nervous system and blood pressure.

• Sedatives, alcohol and sleep medicines: Add to drowsiness.
• Blood pressure and heart medicines: May add to blood pressure lowering effects.
• Certain antidepressants (MAO inhibitors): Should not be combined.
• Oral carbonic anhydrase inhibitors: Avoid combining with the same drug class.

Risks and warnings

• Young children: Not used in infants and young children.
• Drowsiness: The brimonidine part can cause tiredness or low blood pressure.
• Eye allergy: Report redness, itching or swelling that develops over time.
• Heart and vessel disease: Use with caution and inform your doctor.
• Contact lenses: Remove lenses before use.

Simbrinza drops Side Effects

• Blurred vision briefly after use
• Unusual or bitter taste
• Eye redness or irritation
• Dry mouth
• Tiredness

Storage Conditions

Store below 25°C away from direct sunlight; discard four weeks after opening, out of reach of children.