Slate Suspension 250mg/5ml

About Slate Suspension 250mg/5ml

Slate Suspension Uses

• Treats bacterial infections of the respiratory tract, including middle ear infections, throat infections, and bronchitis.
• Manages urinary tract infections caused by susceptible bacteria.
• Treats skin and soft tissue infections in children and adults who need a liquid antibiotic.

Slate Suspension Benefits

• Effective against many common gram positive and some gram negative bacteria.
• A convenient liquid form suitable for young children and anyone who cannot swallow tablets.
• Generally well tolerated with a favorable safety record in pediatric use.
• Flexible two or three times daily dosing schedule.

What Experts Say

Second generation cephalosporins like this one remain a common choice for children with ear, throat, and chest infections because their liquid form makes accurate weight based dosing straightforward for parents. The antibiotic works by interfering with bacterial cell wall formation, which stops the bacteria from multiplying.

Pediatricians usually reserve this class for infections that have not responded to first line options or where a broader spectrum is preferred from the start. Completing the entire course, even once the child seems better, is emphasized repeatedly because stopping early is one of the most common reasons an infection returns or resistance develops.

Respiratory infections remain one of the most frequent reasons Pakistani children visit a doctor, particularly during seasonal changes, which keeps liquid antibiotics like this suspension in steady demand. Refrigerating the mixed suspension and discarding it after the labeled period helps keep the medicine effective for the full course.

Drug Class

• Second-generation Cephalosporin Antibiotic

Slate Suspension 250mg/5ml formula

• Cefaclor Monohydrate

Available forms

• Suspension

How to use Slate Suspension 250mg/5ml?

• Shake the bottle well before every dose.
• Measure the dose using the measuring spoon or oral syringe provided.
• Give with or without food as advised by the doctor.
• Complete the full course even if symptoms improve early.
• Refrigerate the mixed suspension and discard any unused portion after 14 days.

Drug Interactions

• Probenecid: Increases cefaclor blood levels by slowing its clearance from the body.
• Warfarin: May enhance the anticoagulant effect, raising bleeding risk.
• Oral Contraceptives: Cephalosporins may reduce contraceptive effectiveness, so backup protection is advised.
• Live Bacterial Vaccines: Such as the typhoid vaccine, may have reduced effectiveness if given during antibiotic treatment.

Risks and warnings

• Allergic Reaction: Can cause hypersensitivity reactions, especially in patients allergic to penicillin.
• Diarrhea: Prolonged use may lead to Clostridioides difficile associated diarrhea.
• Kidney Impairment: Dose may need adjustment in patients with reduced kidney function.
• Serum Sickness-Like Reaction: Rarely causes joint pain, rash, and fever, more often reported in children.
• Seizure Disorder: Use with caution in patients with a history of seizures.

Slate Suspension Side Effects

• Diarrhea
• Nausea
• Vomiting
• Stomach pain
• Skin rash
• Vaginal itching or discharge
• Eosinophilia
• Rare serum sickness-like reaction with joint pain and fever
• Rare Clostridioides difficile colitis

Storage Conditions

• Store the dry powder below 25°C before mixing.
• Refrigerate the suspension after mixing and use within 14 days.
• Keep the bottle tightly closed and away from moisture.
• Keep out of reach of children.