Sofvasc HCT Tablet 10mg/160mg/12.5mg

About Sofvasc HCT Tablet 10mg/160mg/12.5mg

Sofvasc HCT Tablet Uses

• Essential hypertension not controlled by a single blood pressure medicine
• Blood pressure control in adults already stable on amlodipine and valsartan who need an added diuretic effect
• Long term blood pressure management as part of a heart protection plan

Sofvasc HCT Tablet Benefits

• Three complementary mechanisms in one tablet, a calcium channel blocker, an angiotensin receptor blocker and a diuretic
• A once daily dosing schedule that supports better long term adherence
• A reduced pill burden compared with taking three separate blood pressure medicines

What Experts Say

Amlodipine relaxes blood vessel walls by blocking calcium entry into smooth muscle cells, which widens the arteries. Valsartan blocks the angiotensin II receptor, preventing a hormone that narrows blood vessels and raises blood pressure. Hydrochlorothiazide helps the kidneys remove excess salt and water, lowering overall blood volume and pressure.

Doctors prescribe this triple combination when blood pressure stays high on two drugs alone, a pattern often called resistant hypertension. Combining three mechanisms at fixed doses usually controls blood pressure better than adding drugs one at a time, and it simplifies a patient's daily tablet routine, which improves long term adherence.

High blood pressure affects a large share of adults in Pakistan, and many cases go undiagnosed until a stroke, heart attack or kidney problem occurs. Regular blood pressure checks, along with periodic kidney function and blood salt tests, are advised for anyone taking this triple combination for more than a few months.

Drug Class

• Calcium channel blocker
• Angiotensin receptor blocker
• Thiazide diuretic

Sofvasc HCT Tablet 10mg/160mg/12.5mg formula

• Amlodipine + Valsartan + Hydrochlorothiazide

Available forms

• Tablet

How to use Sofvasc HCT Tablet 10mg/160mg/12.5mg?

• Take the tablet once daily at the same time each day, with or without food.
• Swallow the tablet whole with a glass of water.
• Do not stop the tablet suddenly without talking to your doctor.
• Check your blood pressure regularly while on this medicine.

Drug Interactions

• Potassium Sparing Diuretics: Combined use can raise blood potassium to dangerous levels.
• NSAIDs: Regular use of painkillers like ibuprofen or diclofenac can reduce the blood pressure lowering effect and stress the kidneys.
• Lithium: Reduced clearance of lithium is possible, raising the risk of lithium toxicity.
• Other Blood Pressure Medicines: An additive blood pressure lowering effect is expected when combined with other antihypertensives.

Risks and warnings

• Kidney Function: Kidney function and blood electrolytes should be checked before starting and periodically during treatment.
• Pregnancy: Use in pregnancy is not recommended, since drugs acting on the renin angiotensin system can harm the developing baby.
• Low Blood Pressure: A significant drop in blood pressure is possible in people who are dehydrated or on other blood pressure medicines.
• Gout Risk: A rise in uric acid levels is possible with the thiazide component, which can trigger a gout flare in susceptible people.

Sofvasc HCT Tablet Side Effects

• Dizziness
• Headache
• Swelling of the ankles or feet
• Fatigue
• Low blood pressure on standing up
• Increased urination
• Muscle cramps
• Low potassium levels

Storage Conditions

• Store the tablets at room temperature, below 30°C.
• Keep the strip in its original packaging away from moisture.
• Keep out of reach of children.