Synigan Drops 5ml

About Synigan Drops 5ml

Synigan Uses

• Open-angle glaucoma
• Ocular hypertension (raised eye pressure without glaucoma damage)
• Cases where a single glaucoma eye drop is not enough to control pressure

Synigan Benefits

• Combines two mechanisms in one bottle for stronger pressure control
• Reduces the number of separate eye drops needed daily
• Helps slow vision loss linked to high eye pressure

What Experts Say

Synigan combines two medicines that lower eye pressure through different pathways. Dorzolamide blocks an enzyme called carbonic anhydrase, reducing the fluid produced inside the eye, while timolol is a beta-blocker that also slows down fluid production. Together, they lower intraocular pressure more effectively than either drug used alone.

Eye specialists usually prescribe this combination when a single glaucoma eye drop has not brought pressure down to a safe target level. It is typically used twice daily and requires regular eye pressure checks to confirm the treatment is working and to catch any progression of vision loss early.

Glaucoma often develops silently, with no early symptoms, so many people only discover raised eye pressure during a routine eye checkup or vision test for a new pair of glasses. Because this medicine contains a beta-blocker, people with asthma or heart rhythm problems should always confirm with their doctor before starting it, even though it is applied only to the eye.

Drug Class

• Carbonic anhydrase inhibitor and beta-blocker combination (glaucoma therapy)

Synigan Drops 5ml formula

• Dorzolamide
• Timolol

Available forms

• Eye Drops

How to use Synigan Drops 5ml?

• Tilt your head back and pull down the lower eyelid to form a small pocket.
• Place one drop into the affected eye as prescribed, usually twice daily.
• Press gently on the inner corner of the eye for a minute after application.
• Wait at least 10 minutes before using any other eye drop.

Drug Interactions

• Oral beta-blockers: Using Synigan with oral heart or blood pressure medicines can add to the heart-slowing effect.
• Calcium channel blockers: Combining with certain blood pressure medicines may increase the risk of low heart rate or fainting.
• Other eye drops: Using multiple eye drops together without spacing them apart can wash out the earlier dose before it absorbs.

Risks and warnings

• Heart and lung effects: Timolol can be absorbed into the bloodstream and may slow the heart rate or trigger breathing difficulty in people with asthma or COPD.
• Sulfa sensitivity: Dorzolamide is chemically related to sulfa drugs and may cause a reaction in people with a sulfonamide allergy.
• Contact lens use: The preservative in Synigan can be absorbed by soft contact lenses, so lenses should be removed before application.
• Not for angle-closure glaucoma: This combination is intended for open-angle glaucoma and is not suitable for all types of glaucoma.

Synigan Side Effects

• Burning or stinging when the drop is applied
• Bitter or unusual taste in the mouth
• Blurred vision immediately after use
• Redness or itching of the eye
• Dry eyes
• Headache
• Slow heart rate in sensitive individuals

Storage Conditions

• Store Synigan drops at room temperature, away from direct light.
• Keep the bottle tightly closed when not in use.
• Discard the bottle four weeks after opening.
• Keep out of reach of children.