Tolsura Capsule 100mg

About Tolsura Capsule 100mg

Tolsura Capsule 100mg Uses

• Treatment of fungal nail infections
• Treatment of fungal skin infections like ringworm and pityriasis versicolor
• Treatment of serious fungal infections affecting the lungs or other organs
• Treatment of oral and esophageal fungal infections

Tolsura Capsule 100mg Benefits

• Broad activity against many common and serious fungal infections
• The SUBA formulation improves absorption compared to older itraconazole capsules
• Can be dosed with more flexible food requirements than older formulations
• Effective option when topical antifungal treatments have failed

What Experts Say

Itraconazole is a triazole antifungal that blocks an enzyme fungi need to build ergosterol, an essential part of the fungal cell membrane. Without it, the fungal cell wall becomes weak and unstable, which stops the fungus from growing and spreading.

Dermatologists and physicians in Pakistan prescribe Tolsura Capsule 100mg for stubborn nail fungus, widespread skin fungal infections and more serious fungal infections that need treatment reaching the bloodstream. Course length varies from a few weeks for skin infections to several months for nail infections.

Itraconazole is processed by the liver and can interact with many common medicines, so a full medicine review before starting is important. Patients with heart failure or liver disease need careful evaluation before treatment, since this antifungal has been linked to both conditions in susceptible patients.

Drug Class

• Triazole Antifungal
• Ergosterol Synthesis Inhibitor
• Systemic Antifungal Agent

Tolsura Capsule 100mg formula

• Itraconazole 100mg

Available forms

• Capsule

How to use Tolsura Capsule 100mg?

• Take the capsule exactly as prescribed, with the recommended timing relative to food
• Swallow the capsule whole with a glass of water
• Continue treatment for the full duration prescribed, which may take weeks to months
• Do not stop early even if nails or skin appear to be improving
• Keep follow up appointments so your doctor can monitor liver function and response

Drug Interactions

• Statins: Itraconazole can raise statin levels and increase the risk of muscle damage.
• Certain Heart Medicines: It can interact with some antiarrhythmic and calcium channel blocker drugs, raising the risk of heart rhythm problems.
• Acid Reducing Medicines: Antacids and acid reducing drugs can lower itraconazole absorption depending on the formulation.
• Warfarin: It can enhance the blood thinning effect of warfarin and raise bleeding risk.

Risks and warnings

• Heart Failure: Itraconazole can worsen or trigger heart failure and should be avoided in patients with a history of the condition.
• Liver Damage: Report yellowing of the skin or eyes, dark urine or unusual fatigue, as these can signal liver injury.
• Drug Interactions: It interacts with a wide range of common medicines through the liver, so a full medication review is essential.
• Pregnancy: Should be avoided during pregnancy except for life threatening fungal infections.
• Not Interchangeable: This SUBA formulation is not automatically interchangeable with older itraconazole products at the same milligram dose.

Tolsura Capsule 100mg Side Effects

• Nausea
• Stomach pain
• Headache
• Diarrhea
• Rash
• Fatigue
• Swelling in the legs or ankles
• Raised liver enzymes

Storage Conditions

• Store at room temperature below 30 degrees Celsius
• Keep the capsule strip away from moisture and direct sunlight
• Keep out of reach of children
• Discard the capsule after its printed expiry date