Treviamet Tablet 50mg/850mg

About Treviamet Tablet 50mg/850mg

Treviamet Tablet 50mg/850mg Uses

• Type 2 diabetes when metformin alone does not achieve target blood sugar
• Improving blood sugar control alongside diet and exercise
• Replacing separate vildagliptin and metformin tablets with one combination tablet

Treviamet Tablet 50mg/850mg Benefits

• A combination of two complementary mechanisms of blood sugar control
• Lower risk of low blood sugar compared with sulfonylurea based combinations
• A simpler two drug regimen in a single tablet

What Experts Say

Vildagliptin blocks the DPP-4 enzyme so gut hormones called incretins last longer in the bloodstream, which boosts insulin release only when blood sugar is high and lowers the sugar the liver releases. Metformin works alongside this by reducing how much glucose the liver produces and improving how muscle and fat cells respond to insulin, giving two complementary ways of controlling blood sugar.

Doctors prescribe this fixed dose combination when metformin alone no longer keeps blood sugar in target range, since adding vildagliptin's glucose dependent action lowers blood sugar further without much added risk of a low sugar episode. Combining both drugs into one tablet also reduces the total pill burden for patients managing a chronic condition.

Type 2 diabetes affects a large share of adults across Pakistan, and stepping up from metformin alone to a two drug combination is a common part of long term management. Doctors monitor kidney function regularly during treatment, since both drugs in this combination depend on the kidneys for clearance and dosing may need adjustment over time.

Drug Class

• DPP-4 Inhibitor and Biguanide Combination
• Oral Antidiabetic

Treviamet Tablet 50mg/850mg formula

• Vildagliptin + Metformin Hydrochloride

Available forms

• Tablet

How to use Treviamet Tablet 50mg/850mg?

• Take the tablet with meals to reduce stomach upset.
• Swallow the tablet whole with water, without crushing or chewing it.
• Take doses at the same times each day as prescribed, usually twice daily.
• Continue following your prescribed diet and exercise plan alongside this medicine.
• Do not stop this tablet without your doctor's advice, even if you feel well.

Drug Interactions

• Insulin or Sulfonylureas: Combining with these diabetes medicines raises the risk of low blood sugar.
• Alcohol: Heavy alcohol use increases the risk of lactic acidosis with metformin.
• Contrast Dye: Iodinated contrast used in imaging can raise the risk of kidney injury when combined with metformin.
• ACE Inhibitors: These blood pressure medicines can slightly increase the blood sugar lowering effect of this combination.

Risks and warnings

• Lactic Acidosis: This rare but serious condition can occur with metformin, especially in kidney or liver disease, so warning signs like severe tiredness or muscle pain need urgent attention.
• Kidney Function: Kidney function should be checked before starting and periodically during treatment, since both components are cleared by the kidneys.
• Liver Disease: This tablet should be avoided in significant liver impairment, since vildagliptin has been linked to rare liver enzyme changes.
• Low Blood Sugar: Risk of low blood sugar rises when combined with insulin or a sulfonylurea.
• Pancreatitis: The medicine should be stopped and care sought if severe abdominal pain suggests pancreatitis.
• Contrast Dye Procedures: This tablet is usually paused around procedures using iodinated contrast dye, due to kidney injury risk.

Treviamet Tablet 50mg/850mg Side Effects

• Nausea or stomach upset
• Diarrhea
• Loss of appetite
• Headache
• Dizziness
• Low blood sugar when combined with insulin or a sulfonylurea
• Metallic taste in the mouth

Storage Conditions

• Store the tablets at room temperature, below 30°C.
• Keep the strip in its original packaging away from moisture.
• Protect from direct sunlight and heat.
• Keep out of reach of children.