Ultrame Plus Tablet 5mg / 325mg

About Ultrame Plus Tablet 5mg / 325mg

Ultrame Plus Tablet 5mg / 325mg Uses

• Relieves moderate to moderately severe pain
• Treats postoperative pain
• Treats pain from injuries and musculoskeletal conditions
• Treats dental pain
• Used for pain that does not respond adequately to paracetamol alone

Ultrame Plus Tablet 5mg / 325mg Benefits

• Combines an opioid pain reliever with paracetamol for stronger combined pain relief
• Allows a lower opioid dose than using tramadol alone for similar pain relief
• Fast acting formulation suitable for short term pain management
• Convenient two in one tablet reduces the number of separate pills needed

What Experts Say

Tramadol relieves pain by acting on opioid receptors in the brain and spinal cord while also affecting serotonin and noradrenaline pathways involved in pain signaling, and paracetamol adds a separate pain relieving and fever reducing effect. Combining the two allows effective pain control while keeping the opioid dose in each tablet comparatively low.

Doctors generally prescribe this combination for short courses of moderate pain rather than long term use, since tramadol carries a risk of dependence and tolerance with extended use. Patients are usually advised to take the lowest effective dose for the shortest period needed to control symptoms.

Clinicians watch for the total daily paracetamol dose across all medicines a patient is taking, since exceeding the safe limit can cause serious liver injury. Tramadol also carries a seizure risk at higher doses and a serotonin syndrome risk when combined with certain antidepressants, so a full medication history is reviewed before prescribing.

Drug Class

• Opioid analgesic combination

Ultrame Plus Tablet 5mg / 325mg formula

• Tramadol + Paracetamol

Available forms

• Tablet

How to use Ultrame Plus Tablet 5mg / 325mg?

• Take exactly as prescribed by your doctor, do not increase the dose on your own
• Swallow the tablet whole with a glass of water
• Take with food if it causes stomach upset
• Do not take other paracetamol containing products while using this medicine
• Do not stop a longer course suddenly without medical advice

Drug Interactions

• Antidepressants (SSRIs, SNRIs): Combined use raises the risk of serotonin syndrome
• Other Opioids: Increases the risk of sedation and breathing problems when combined
• Alcohol: Increases drowsiness and the risk of breathing difficulty
• Warfarin: May increase bleeding risk and requires closer monitoring
• Other Paracetamol Containing Products: Combining raises the risk of exceeding the safe daily paracetamol limit and liver damage

Risks and warnings

• Liver Disease: Avoid or use with caution due to the paracetamol content and risk of liver injury
• Seizure Disorder: Use with caution as tramadol can lower the seizure threshold
• Dependence: Carries a risk of tolerance and dependence with prolonged use, so use only as directed
• Respiratory Conditions: Use cautiously in patients with breathing problems since opioids can slow breathing
• Serotonin Syndrome: Risk increases when combined with certain antidepressants or other serotonin affecting medicines

Ultrame Plus Tablet 5mg / 325mg Side Effects

• Nausea
• Dizziness
• Drowsiness
• Constipation
• Dry mouth
• Sweating
• Headache
• Slowed breathing at higher doses
• Seizures in rare cases
• Severe allergic reaction in rare cases

Storage Conditions

• Store below 30 degrees Celsius in a dry place away from light
• Keep the tablet in its original blister pack until use
• Keep out of reach of children in a secure location due to opioid content
• Do not use after the printed expiry date