Utrogestan Tablet 100mg

About Utrogestan Tablet 100mg

Utrogestan Tablet 100mg Uses

• Supports the luteal phase during IVF and other assisted fertility treatments
• Helps prevent threatened or recurrent miscarriage linked to low progesterone
• Used in hormone replacement therapy for women with an intact uterus
• Treats progesterone deficiency causing irregular or absent periods
• Manages secondary amenorrhea by restoring a normal menstrual cycle

Utrogestan Tablet 100mg Benefits

• Uses a natural, body identical form of progesterone rather than a synthetic analogue
• Can be given orally or vaginally depending on the treatment plan
• Supports embryo implantation during fertility treatment cycles
• Protects the uterine lining when combined with estrogen in HRT
• Well studied safety profile with decades of clinical use worldwide

What Experts Say

Fertility specialists rely on micronized progesterone such as Utrogestan Tablet 100mg to support the luteal phase after ovulation induction or embryo transfer. Natural progesterone keeps the uterine lining receptive, which doctors consider central to successful implantation during assisted reproduction cycles.

Dosing is never one size fits all. IVF cycles usually need higher, more frequent doses timed tightly around egg retrieval and transfer, while routine hormone replacement therapy follows a steadier, lower dose schedule. Physicians also choose the oral or vaginal route based on how well a patient tolerates drowsiness or absorbs the medicine.

Pakistan's fertility treatment sector has expanded steadily in recent years, with more couples now pursuing IVF and other assisted reproduction options. This growth has made accurate, guideline based use of progesterone support medicines like Utrogestan increasingly relevant for both specialists and general practitioners managing early pregnancy care.

Drug Class

• Progestin (natural progesterone hormone)
• Used as part of hormone replacement therapy and fertility treatment protocols

Utrogestan Tablet 100mg formula

• Progesterone

Available forms

• Tablet

How to use Utrogestan Tablet 100mg?

• Swallow the capsule whole with water when taken by the oral route, usually at bedtime since drowsiness can occur
• For vaginal use, insert the capsule deep into the vagina as directed by the treating doctor, often chosen for luteal phase support in IVF
• IVF cycle dosing is typically higher and given at closely timed intervals around egg retrieval and embryo transfer
• Standard hormone replacement therapy dosing follows a steadier, lower daily schedule than an IVF cycle
• Take doses at the same time each day to maintain a consistent hormone level
• Do not stop the medicine suddenly without consulting the prescribing doctor, especially during early pregnancy support

Drug Interactions

• Ketoconazole: This antifungal can raise progesterone levels by slowing its breakdown in the liver
• Rifampicin: This antibiotic can lower progesterone levels by speeding up its breakdown, reducing effectiveness
• Anticonvulsants: Medicines like phenytoin and carbamazepine can reduce progesterone levels through enzyme induction
• Sedatives And Tranquilizers: Combining with other sedating medicines can increase drowsiness, especially with the oral route
• St John's Wort: This herbal supplement can lower progesterone levels by increasing its metabolism

Risks and warnings

• Blood Clot Risk: Progesterone therapy can slightly raise the risk of blood clots in the legs or lungs, especially in women with other clotting risk factors
• Liver Disease: Avoid use in significant liver impairment since the liver processes progesterone and reduced function can raise drug levels
• Undiagnosed Vaginal Bleeding: Report any unexplained vaginal bleeding to a doctor before starting, since it needs to be investigated first
• Breast Cancer History: Use with caution in women with a personal or strong family history of breast cancer, under close specialist supervision
• Drowsiness With Oral Route: Oral capsules can cause noticeable drowsiness or dizziness, so bedtime dosing and caution with driving are advised
• Pregnancy Monitoring: Use only under a doctor's supervision during pregnancy, with regular monitoring as advised by the treating specialist

Utrogestan Tablet 100mg Side Effects

• Drowsiness or dizziness, mainly with the oral route
• Headache
• Breast tenderness
• Bloating or mild fluid retention
• Nausea
• Mood changes or irritability
• Spotting or irregular vaginal bleeding
• Vaginal irritation or discharge with the vaginal route
• Fatigue
• Signs of a blood clot such as leg swelling, pain or sudden breathlessness need urgent medical attention
• Severe allergic reaction with rash, swelling or difficulty breathing is rare but needs emergency care

Storage Conditions

• Store below 25°C in a cool, dry place away from direct sunlight
• Keep the capsules in their original blister pack until the dose is due
• Keep out of reach of children
• Do not store in the bathroom or near a sink where moisture can damage the capsules
• Discard any unused capsules after the expiry date printed on the pack