Vendep Tablet 37.5mg

About Vendep Tablet 37.5mg

Vendep Tablet 37.5mg Uses

• Major depressive disorder (clinical depression)
• Generalized anxiety disorder
• Social anxiety disorder (social phobia)
• Panic disorder

Vendep Tablet 37.5mg Benefits

• Improves low mood and restores interest in daily activities
• Reduces excessive worry and anxious thoughts
• Helps regulate sleep and appetite disturbed by depression
• Lowers the frequency of panic attacks over time

What Experts Say

Venlafaxine works by blocking the reuptake of serotonin and norepinephrine in the brain. At higher doses, it also has a mild effect on dopamine reuptake. This dual action increases the availability of these mood regulating neurotransmitters at nerve synapses, which helps correct the chemical imbalance associated with depression and anxiety disorders.

Clinical response usually takes two to four weeks to become noticeable, since neurotransmitter receptors need time to adjust to the higher chemical availability. Doses are typically started low and increased gradually to reduce side effects and allow the body to adapt. Missing this titration step can raise the risk of nausea, dizziness, or a spike in blood pressure.

Because venlafaxine affects norepinephrine as well as serotonin, it carries a modest risk of raising blood pressure, unlike medicines that act on serotonin alone. Stopping the drug abruptly can trigger dizziness, irritability, and flu like symptoms, so tapering under medical guidance is standard practice.

Drug Class

• Serotonin Norepinephrine Reuptake Inhibitor (SNRI)

Vendep Tablet 37.5mg formula

• Venlafaxine

Available forms

• Tablet

How to use Vendep Tablet 37.5mg?

• Take Vendep tablet exactly as prescribed by your doctor, usually once or twice daily
• Swallow the tablet whole with a full glass of water, do not crush or chew it
• Take at the same time each day, preferably with food to reduce stomach upset
• Do not stop taking this medicine suddenly without consulting your doctor
• Continue the course for the full duration even if you start feeling better

Drug Interactions

Vendep Tablet 37.5mg can interact with several other medicines, so tell your doctor about everything you are taking.

• MAOIs: Must not be combined with monoamine oxidase inhibitors due to a high risk of serotonin syndrome, a gap of at least 14 days is required when switching
• SSRIs And Other Serotonergic Drugs: Increases the risk of serotonin syndrome when combined with other antidepressants or migraine medicines like triptans
• Tramadol: Raises the risk of serotonin syndrome and seizures when used together
• NSAIDs, Aspirin And Warfarin: May increase the risk of bleeding when combined with venlafaxine
• CYP2D6 Inhibitors: Drugs like ketoconazole can raise venlafaxine blood levels and increase side effects

Risks and warnings

• Suicidal Thoughts: Monitor closely for worsening mood or new suicidal thoughts, especially in the first few weeks of treatment or after a dose change
• Blood Pressure: Regular blood pressure checks are advised since venlafaxine can raise blood pressure at higher doses
• Discontinuation Syndrome: Stopping the medicine abruptly can cause dizziness, irritability, and flu like symptoms, so doses should be tapered gradually
• Serotonin Syndrome: Combining with other serotonergic medicines raises the risk of this serious condition marked by agitation, fever, and rapid heartbeat
• Pregnancy And Breastfeeding: Use only if clearly needed and under close medical supervision, since venlafaxine crosses into breast milk

Vendep Tablet 37.5mg Side Effects

Vendep Tablet 37.5mg is generally well tolerated when used as directed, though some effects can still appear.

• Nausea
• Dry mouth
• Dizziness
• Insomnia or unusual dreams
• Excessive sweating
• Constipation
• Loss of appetite
• Sexual dysfunction
• Headache
• Blurred vision
• Fatigue or drowsiness

Contact your doctor immediately if any of these serious reactions occur.

• Increased blood pressure
• Signs of serotonin syndrome such as agitation, rapid heartbeat, or high fever (rare)

Storage Conditions

• Store below 30°C in a cool, dry place away from moisture
• Keep the tablet strip in its original packaging until use
• Protect from direct sunlight and heat
• Keep out of reach of children