Zonlac Injection

About Zonlac Injection

Zonlac Injection Uses

• Short-term relief of moderate to severe pain after surgery
• Pain management following major trauma or injury
• Relief of acute kidney stone (renal colic) pain
• Postoperative pain when oral medicines are not practical
• Bridge therapy before switching to oral pain relief

Zonlac Injection Benefits

• Fast-acting pain relief given directly into muscle or vein
• Effective non-opioid alternative for severe acute pain
• Reduces need for repeated opioid dosing after surgery
• Useful when patients cannot swallow tablets after an operation
• Strong anti-inflammatory action alongside pain relief

What Experts Say

Doctors turn to Zonlac when a patient needs strong, fast pain relief without using opioids. Ketorolac tromethamine blocks prostaglandin production, easing inflammation and pain after surgery, trauma or kidney colic, and its injectable form starts working faster than oral tablets during acute severe pain episodes in a hospital setting.

Post-surgical and trauma pain management is common in Pakistani hospitals, where injectable NSAIDs are favored for quick relief when oral intake is delayed right after an operation or accident. Cost also matters, since many families cannot afford repeated opioid doses, making a short course of ketorolac a practical and widely used hospital option.

Ketorolac is meant only for short-term use, typically not beyond five days including any oral therapy that follows it. Doctors monitor kidney function, stomach discomfort and bleeding tendency closely during treatment, since prolonged use raises the risk of ulcers, gastrointestinal bleeding and reduced kidney function significantly.

Drug Class

• Non-steroidal anti-inflammatory drug (NSAID)
• Analgesic, injectable

Zonlac Injection formula

• Ketorolac Tromethamine 30mg

Available forms

• Injection

How to use Zonlac Injection?

• To be administered only by a qualified healthcare professional
• Given by intramuscular (IM) or intravenous (IV) injection as directed
• Usual course does not exceed five days total, including any oral follow-up
• Dose and frequency are adjusted based on age, weight and kidney function
• Not intended for self-administration at home

Drug Interactions

Zonlac Injection can interact with other medicines, so the treating doctor must know your full medication list.

• Other NSAIDs (ibuprofen, diclofenac, aspirin): Combined use raises the risk of stomach bleeding and ulcers.
• Blood thinners (warfarin, heparin): Increases the risk of serious bleeding.
• ACE inhibitors or ARBs: May reduce their blood pressure lowering effect and stress the kidneys.
• Lithium: Ketorolac can raise lithium levels to a toxic range.
• Corticosteroids: Combined use further increases the risk of gastrointestinal ulceration.

Risks and warnings

• Bleeding risk: Increases bleeding tendency, so it is avoided before or during surgery with high bleeding risk.
• Stomach ulcers: Can cause or worsen gastrointestinal ulcers and bleeding, especially with prolonged use.
• Kidney impairment: Should be avoided or used cautiously in patients with reduced kidney function.
• Pregnancy: Not recommended, particularly in the third trimester, due to risk to the baby.
• Duration limit: Must not be used for more than five days combined with oral ketorolac therapy.

Zonlac Injection Side Effects

Some side effects can occur even when the injection is given correctly under medical supervision.

• Pain or swelling at the injection site
• Nausea or stomach upset
• Headache
• Dizziness
• Drowsiness
• Dry mouth

Contact your doctor or seek medical help if you notice any of the following serious effects.

• Black or bloody stools, or vomiting blood
• Severe stomach pain
• Signs of an allergic reaction such as rash, swelling or breathing difficulty
• Very low urine output or swelling in the legs
• Unusual bruising or bleeding

Storage Conditions

• Store below 25°C, protected from light
• Do not freeze the ampoules or vials
• Keep in the original packaging until ready for use
• Use only clear, particle-free solution; discard if discolored
• Keep out of reach of children and handle only in a clinical setting