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Everything you need to know about Brexin in Pakistan

Dr. Hira Tanveer

4 min read

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What is Brexin?

Brexin is a Piroxiam, which is a type of painkiller that also carries some anti-inflammatory properties. It works by stopping the production of chemical mediators that cause pain and inflammation in the body. 

It is used to treat a wide range of ailments; from the more serious to arthritis to less grave menstrual cramps, Brexin addresses various health issues. 

Brexin Formula:

Brexin is composed essentially of Piroxicam beta-cyclodextrin.

What are the Available Forms of Brexin in Pakistan?

There are mainly two forms of Brexin available in Pakistan. One is a tablet, which is yellow with hexagonal scoring in the middle. Another form is white crystalline powder, available in the form of a sachet. 

Brexin Dosage and Strength: 

Following are the dosage strengths available for Brexin: 

  • Tablet as 20mg
  • Sachet as 20mg

The precise dosage required by the patient is determined by the. It will depend on the pain and the need of the patients. However, for adults, the recommended dosage is 20mg per day. 

How to take Brexin?

Swallow the tablet whole; do not crush or chew the tablet. Moreover, you should not take Brexin on an empty stomach, as it can upset your stomach and lead to gastric ulcers as well. 

In case you feel stomach pain and nausea in aftermath of taking Brexin, you should inform your healthcare provider as it may be a sign of gastritis. To avoid getting gastritis, take Brexin for the shortest time possible. 

What are the Uses of Brexin?

  • Pain due to arthritis and osteoarthritis
  • Menstrual cramps
  • Joint pain
  • Migraine
  • Pain associated with gout
  • Muscle spasm
  • To get rid of mild to moderate fever
  • Bone pain
  • Ankylosing spondylitis
  • Tendonitis
  • Sprains
  • Pain associated with fractures
  • Back pain
  • Pain due to frozen shoulder
  • Neck pain
  • Bursitis

What are the side effects of Brexin?

Drugs help the body against several ailments, but they also carry some drawbacks, and Brexin is no exception. Its side-effects include:

  • Abdominal pain
  • Vomit containing coffee grounds
  • Blood in stool
  • Constipation
  • Black stools
  • Acid reflux

What are the risks and warnings for Brexin?

Allergic to Brexin

People who are allergic to Piroxicam should not use Brexin, or medicines with the same generic name. An allergic reaction may be mild, causing wheezing or rashes, etc., but it can be life-threatening as well. 

An extreme form of an allergic reaction, anaphylactic shock, can be fatal as well if the antidote is not administered in time. Therefore, disclose all your allergies to your healthcare provider, so the risk of anaphylaxis is minimized. 

Heart diseases 

People with heart disease or a history of heart attack should use Brexin with caution. It inhibits the production of prostaglandins, which is a chemical that protects the heart. 

Stroke 

People with a history of stroke should not take Brexin, as it can increase their chances of getting another episode of it. 

Hypertension 

Patients diagnosed with hypertension should use the tablets or the sachets of Brexin with caution. 

Brexin causes water retention in the body, and thus increases the volume of blood, which is an alarming state for hypertensive patients. 

Congestive heart failure

Individuals suffering from congestive heart failure should take Brexin with caution. In their condition, their heart is already struggling to efficiently pump blood around the body. Adding the water retention caused by Brexin to mix complicates the condition then. 

Edema

People with edema –swelling in the body –should take Brexin with caution. Edema is aggravated by water retention in the body, and as Brexin causes it, people need to be careful with their Brexin consumption. 

Gastric ulcers

Brexin inhibits the production of chemicals that protect the lining of the stomach. Thus, people suffering from gastritis and acidity should take Brexin with caution, as it can aggravate their symptoms. 

Long-term use of Brexin can cause ulceration in the lining of the stomach, which is why your doctor may have to prescribe a gastroprotective agent alongside Brexin. 

Anticoagulants or bleeding disorders

If you suffer from bleeding disorders or use anticoagulants for thinning blood, you should take Brexin with care.

Brexin inhibits the production of chemicals in the body that is responsible for making clotting factors. Since the same purpose is served by anticoagulants, taking them with Brexin can compound this effect in the body. Consequently, there is an increased risk of bleeding on account of the increased anticoagulant action. 

Kidney disease

People suffering from kidney disease need to exercise extreme caution when using Brexin, as long-term usage of Brexin increases the risk of kidney impairment. 

Asthma 

Since Brexin can precipitate existing cases of asthma, asthmatic people should take it with caution. 

Liver diseases

Those suffering from liver disease should take Brexin at the discretion of their doctor. The liver performs the task of metabolism and excretion of drugs. When its function is impaired, drugs get accumulated in the body that can have grave implications on the person’s health

Pregnancy and breastfeeding

Women who are pregnant should not take Brexin unless approved by their doctor. Brexin can endanger the heart of the baby, especially when taken during the third trimester. 

 Similarly, women who are breastfeeding should not take Brexin, unless advised otherwise by their doctor. 

Interactions between Brexin and other medications:

Brexin can interact with other drugs that you might be taking. A drug interaction does not mean that you decide to stop taking the medicines. Instead, you should consult your healthcare provider about it. 

Drugs that Brexin can interact with include:

  • ACE inhibitors like captopril, fosinopril and enalapril, etc
  • Angiotensin receptor blockers like losartan, valsartan etc
  • Corticosteroids like prednisolone
  • Potassium supplements
  • Aspirin
  • Lithium 
  • Blood thinners like clopidogrel, enoxaparin, warfarin, etc.

To prevent a case of drug interaction, patients are advised to give their detailed medical history to their healthcare provider. A readjustment of dosage or time for the medicine can help avoid this interaction. 

What is the price of Brexin in Pakistan?

The price of one tablet of Brexin in Pakistan is Rs. 43/-. 

Storage Conditions:

  • Brexin should be kept out of reach and sight of children.
  • It should be stored at room temperature.
  • The medicine should not be used after the expiration date has passed.

How to get Brexin in Pakistan?

Brexin is not an over-the-counter drug. You need to have a valid prescription from the doctor to get Brexin. 

It is pertinent that you present your latest prescription to your pharmacist to enable the purchase of the drug.

What medicines are available as alternatives to Brexin in Pakistan?

Following drugs serve as alternatives to Brexin: 

  • Feldene
  • Hocam
  • Feldicam

Conclusion:

Brexin is a painkiller that also carries some anti-inflammatory properties that cater to a wide range of ailments. Brexin is mostly used to moderate the pain in the musculoskeletal system caused by conditions like arthritis, bursitis, tendonitis, etc. 

It also helps treat other aches in the body, like migraines, period cramps, backache. Brexin can also also be used in the treatment of fever. 

However, Brexin also carries side effects, especially when used over a long period. Therefore, you must use it only as per the instructions of the doctor. 

In order to consult a doctor before using Brexin, make sure to use oladoc or call (042) 38900939 and get the best expert counseling while availing up to a 50 percent discount on your appointments. 

Disclaimer: The contents of this article are intended to raise awareness about common health issues and should not be viewed as sound medical advice for your specific condition. You should always consult with a licensed medical practitioner prior to following any suggestions outlined in this article or adopting any treatment protocol based on the contents of this article.

Dr. Hira Tanveer - Author Dr. Hira Tanveer is among the Best General Physicians in Lahore. Dr. Hira Tanveer is an MBBS doctor and currently serving at CMH Lahore. Writing is her favorite hobby as she loves to share professional advice on trendy healthcare issues, general well-being, healthy diet, and lifestyle.
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