A2A Tablet 25mg

About A2A Tablet 25mg

A2A Tablet Uses

• Treating high blood pressure in adults.
• Protecting the kidneys in people with type 2 diabetes and diabetic kidney disease.
• Reducing the risk of stroke in patients with high blood pressure and thickening of the heart's left chamber.

A2A Tablet Benefits

• Lowers blood pressure effectively with once daily dosing.
• Slows the progression of kidney damage in diabetic patients.
• Generally well tolerated with a low risk of persistent dry cough compared to older blood pressure medicines.
• Can be combined safely with other blood pressure medicines when needed.

What Experts Say

Losartan blocks angiotensin II from binding to receptors in blood vessels, which relaxes the vessel walls and lowers blood pressure. Physicians often choose an angiotensin receptor blocker like losartan for patients who develop a persistent dry cough with older ACE inhibitor medicines.

Dosing usually starts at a low strength and is adjusted over several weeks based on repeated blood pressure readings and periodic kidney function tests. This gradual approach helps avoid a sudden drop in blood pressure, particularly in elderly or dehydrated patients, and allows the body to adapt smoothly.

Routine monitoring of kidney function, electrolytes, and blood potassium levels is recommended, especially in patients with diabetes or preexisting kidney disease. In Pakistan, physicians frequently pair losartan with lifestyle changes such as reduced salt intake, weight control, and regular exercise, since diet plays a major role in blood pressure control across this population.

Drug Class

• Angiotensin II Receptor Blocker
• Antihypertensive Agent

A2A Tablet 25mg formula

• Losartan Potassium

Available forms

• Tablet

How to use A2A Tablet 25mg?

• Take one tablet by mouth, usually once daily, with or without food.
• Swallow the tablet whole with a glass of water.
• Take it at the same time each day to maintain a steady effect.
• Do not stop the medicine suddenly without consulting a doctor, even if blood pressure feels normal.
• Inform your doctor if you become pregnant while taking this medicine.

Drug Interactions

• Potassium Sparing Diuretics: Combined use can raise blood potassium to dangerous levels.
• NSAIDs: Regular use can reduce the blood pressure lowering effect and affect kidney function.
• Lithium: Losartan can increase blood lithium levels and raise the risk of toxicity.
• ACE Inhibitors: Combining with another blood pressure medicine of a similar class increases the risk of kidney problems and high potassium.
• Rifampin: Can reduce the effectiveness of losartan by increasing its breakdown in the liver.

Risks and warnings

• Pregnancy Risk: Can cause serious harm to an unborn baby, especially in the second and third trimester, and must be stopped as soon as pregnancy is confirmed.
• High Potassium Levels: May raise blood potassium, particularly in patients with kidney disease or those taking potassium supplements.
• Low Blood Pressure: Can cause dizziness or fainting, especially after the first dose or in patients who are dehydrated.
• Kidney Function Changes: Requires monitoring in patients with existing kidney impairment or those on diuretics.
• Liver Impairment: Needs a lower starting dose and closer monitoring in patients with liver disease.

A2A Tablet Side Effects

• Dizziness, especially when standing up quickly.
• Fatigue and general tiredness.
• Headache.
• Diarrhea or upset stomach.
• Nasal congestion or upper respiratory symptoms.
• Muscle cramps or back pain.
• High potassium levels detected on blood tests.
• Low blood pressure symptoms such as lightheadedness or fainting.
• Swelling of the face, lips, or throat in rare allergic reactions.
• Changes in kidney function seen on lab tests.

Storage Conditions

• Store tablets at room temperature below 30 degrees Celsius.
• Keep the strip in its original packaging away from moisture.
• Protect from direct sunlight and humidity.
• Keep out of reach of children.
• Discard any tablets past their printed expiry date.