Acetin Capsule 25mg

About Acetin Capsule 25mg

Acetin Capsule 25mg Uses

• Severe plaque psoriasis
• Pustular psoriasis
• Erythrodermic psoriasis
• Palmoplantar psoriasis affecting hands and feet
• Darier's disease

Acetin Capsule 25mg Benefits

• Reduces thick scaling and plaque buildup
• Slows abnormal skin cell turnover
• Effective for psoriasis resistant to creams
• Can reduce the need for stronger systemic therapy

What Experts Say

Acetin contains acitretin, an oral retinoid derived from vitamin A. It works by slowing down the rapid turnover of skin cells that causes the thick, scaly plaques seen in severe psoriasis. Dermatologists reserve it for cases that have not responded well to creams or light therapy alone, and it can also help pustular and palm and sole psoriasis.

Because acitretin stays in the body for a long time and can cause serious birth defects, doctors run pregnancy tests before starting treatment in women of childbearing age. Regular blood tests for liver function and cholesterol are also part of routine monitoring throughout the course of therapy.

Dermatology clinics here typically start this medicine only after confirming a patient understands the strict contraception rules that must continue for three years after stopping treatment, given how often it is requested for stubborn plaque psoriasis during dry winter months across many cities.

Drug Class

• Oral retinoid

Acetin Capsule 25mg formula

• Acitretin

Available forms

• Capsule

How to use Acetin Capsule 25mg?

• Take the capsule exactly as prescribed by your dermatologist.
• Swallow with a meal or milk to improve absorption.
• Do not increase or stop the dose without medical advice.
• Attend all scheduled blood tests during treatment.
• Use effective contraception as advised for the full treatment period and beyond.

Drug Interactions

• Methotrexate: Combined use raises the risk of serious liver toxicity.
• Vitamin A supplements: Taking these together increases the risk of vitamin A toxicity symptoms.
• Alcohol: Alcohol must be avoided since it prolongs the drug's presence in the body.
• Tetracycline antibiotics: Combined use raises the risk of increased pressure around the brain.
• Contraceptive pills: Low dose progesterone only pills may be less reliable during treatment.

Risks and warnings

• Pregnancy: Acitretin causes severe birth defects and must be avoided during pregnancy and for three years after stopping.
• Liver function: Regular liver enzyme monitoring is required during treatment.
• Cholesterol levels: It can raise blood triglycerides and cholesterol significantly.
• Blood donation: Patients must not donate blood during treatment or for three years afterward.
• Alcohol: Alcohol can convert acitretin into a longer lasting, more harmful compound.
• Bone changes: Long term use has been linked to bone density changes with prolonged therapy.

Acetin Capsule 25mg Side Effects

• Dry lips and skin
• Hair thinning
• Dry eyes
• Nosebleeds
• Peeling skin on palms and soles
• Raised cholesterol levels
• Joint aches
• Nail changes

Storage Conditions

• Store below 25 degrees Celsius in a cool, dry place.
• Keep the capsules in their original blister strip away from light.
• Protect from moisture and direct heat.
• Discard capsules after the printed expiry date.
• Keep out of reach of children.