About Adenuric Tablet 80mg
Adenuric Tablet 80mg contains Febuxostat, a xanthine oxidase inhibitor used to treat chronic gout.
Adenuric Tablet 80mg Uses
- Treats chronic gout caused by high uric acid levels
- Lowers blood uric acid in patients with recurring gout attacks
- Used for long term uric acid control in tophaceous gout
- Prescribed when allopurinol is not tolerated or not effective
Adenuric Tablet 80mg Benefits
- Reduces the frequency of painful gout flares over time
- Shrinks uric acid deposits called tophi with continued use
- Works even in patients with mild to moderate kidney impairment
- Once daily dosing makes it easier to stay consistent with treatment
What Experts Say
Doctors in Pakistan increasingly prescribe Adenuric Tablet 80mg for chronic gout when allopurinol, the older first line urate lowering drug, is not tolerated or fails to bring uric acid to target. Rising red meat and seafood consumption, obesity and chronic kidney disease have pushed gout rates higher across the country.
International drug regulators, including the FDA, added a boxed warning to febuxostat after a large cardiovascular outcomes trial linked it to a higher rate of heart related deaths compared with allopurinol. Physicians now reserve this tablet mainly for patients who have already tried allopurinol, and they screen for existing heart disease before starting treatment and monitor closely afterward.
Starting febuxostat can trigger a temporary gout flare as stored uric acid crystals are mobilized from the joints, so doctors commonly add a low dose NSAID or colchicine for the first few months. Liver function tests are checked before treatment starts and periodically during therapy since the drug is processed by the liver.
Drug Class
- Xanthine Oxidase Inhibitor
Adenuric Tablet 80mg Uses in Urdu
- یورک ایسڈ کی زیادہ مقدار کی وجہ سے ہونے والے گاؤٹ کا علاج
- خون میں یورک ایسڈ کی سطح کم کرنے کے لیے استعمال
- بار بار ہونے والے گاؤٹ کے حملوں کو روکنے کے لیے
- ایسے مریضوں کے لیے جو ایلوپیورینول برداشت نہیں کر سکتے
Adenuric Tablet 80mg formula
How to use Adenuric Tablet 80mg?
- Take Adenuric Tablet 80mg once daily with or without food
- Swallow the tablet whole with a full glass of water
- Take it at the same time every day for best results
- Continue treatment even after a gout attack settles, unless your doctor advises otherwise
- Drink plenty of water daily while on this medicine
- Do not stop the tablet suddenly without talking to your doctor
Drug Interactions
- Azathioprine: Combining with Adenuric Tablet 80mg can cause dangerous bone marrow suppression and is generally avoided
- Mercaptopurine: Febuxostat blocks the enzyme that breaks this drug down, raising toxicity risk to a dangerous level
- Theophylline: High doses of febuxostat may raise theophylline blood levels, needing monitoring
- NSAIDs: Often used together for flare prevention, but long term use needs monitoring for stomach and kidney effects
- Colchicine: Commonly combined during the first months of treatment to prevent gout flares under medical supervision
Risks and warnings
- Cardiovascular Risk: Febuxostat carries a boxed warning for a higher risk of heart related death compared with allopurinol, so it is generally reserved for patients who cannot use allopurinol
- Gout Flare At Start: Lowering uric acid can trigger a temporary increase in gout attacks during the first few months of treatment
- Liver Problems: Can raise liver enzymes, so liver function should be checked before and during treatment
- Heart Disease History: Use with caution in patients with a history of heart attack, stroke or heart failure
- Kidney Impairment: Dose adjustment may be needed in patients with significant kidney disease
- Allergic Reaction: Stop the tablet and seek medical help if rash, swelling or difficulty breathing occurs
- Pregnancy And Breastfeeding: Not recommended unless clearly advised by a doctor since safety data is limited
Adenuric Tablet 80mg Side Effects
- Nausea
- Joint pain
- Increased liver enzymes
- Rash
- Headache
- Diarrhea
- Gout flare during early treatment
- Dizziness
- Swelling in the hands or feet
- Chest pain or irregular heartbeat, requiring urgent medical attention
Storage Conditions
- Store Adenuric Tablet 80mg at room temperature below 30 degrees Celsius
- Keep the blister pack in its original box away from direct sunlight
- Protect from moisture and keep in a dry place
- Keep out of reach of children
- Do not use after the expiry date printed on the pack
