Adgen Tablet 10mg

About Adgen Tablet 10mg

Uses

• Treats chronic hepatitis B infection in adults
• Used in people with signs of active liver disease from hepatitis B
• Helps lower hepatitis B virus levels in the blood
• Used for hepatitis B with compensated or decompensated liver disease under specialist care
• Sometimes used for hepatitis B strains resistant to other antivirals

Benefits

• Slows down liver damage caused by long term hepatitis B infection
• Reduces the amount of virus circulating in the blood
• Once daily dosing makes it easier to stay consistent with treatment

What Experts Say

Adefovir dipivoxil is a nucleotide analogue medicine. Once inside the body it changes into its active form and blocks the enzyme that hepatitis B virus needs to copy its genetic material, which slows down the virus and reduces liver damage over time.

Liver specialists across Lahore, Karachi, Islamabad and Rawalpindi prescribe it for adults with chronic hepatitis B who show ongoing signs of liver damage. Treatment usually continues for a long period, sometimes years, and doctors track viral load and liver enzyme levels every few months to judge how well it is working.

Kidney function needs regular monitoring during treatment, since this medicine can affect the kidneys, especially with long term use in older adults. Stopping the medicine suddenly can trigger a serious flare up of hepatitis, so any change in dose or stopping treatment always needs medical guidance.

Drug Class

• Nucleotide reverse transcriptase inhibitor (antiviral)

Adgen Tablet 10mg formula

• Adefovir Dipivoxil

Available forms

• Tablet

How to use Adgen Tablet 10mg?

• Take one tablet by mouth once a day, at the same time each day
• Can be taken with or without food
• Swallow the tablet whole with water
• Do not stop the medicine suddenly without talking to your doctor
• Attend all scheduled blood tests to monitor liver and kidney function

Drug Interactions

• Other Kidney Affecting Drugs: Combining with other medicines that affect the kidneys increases the risk of kidney damage
• Tenofovir: Should not be combined, since both drugs work similarly and increase toxicity risk
• NSAIDs: Regular use together may raise the risk of kidney problems

Risks and warnings

• Kidney Disease: Requires dose adjustment and regular kidney function monitoring
• Sudden Discontinuation: Stopping this medicine abruptly can cause a serious hepatitis flare up
• Liver Disease: Use with caution in people with severe liver impairment
• Pregnancy And Breastfeeding: Use only if clearly needed and under specialist supervision
• Bone Health: Long term use has been linked to bone softening in some patients

Adgen Tablet Side Effects

• Nausea
• Weakness or fatigue
• Headache
• Abdominal pain
• Diarrhea
• Reduced kidney function with long term use
• Bone pain or softening (rare)
• Lactic acidosis, a serious buildup of acid in the blood (rare)
• Severe liver flare up after stopping treatment (rare)

Storage Conditions

• Store below 30°C in a cool, dry place
• Keep the tablets in their original container
• Protect from moisture and direct sunlight
• Keep out of reach of children