About Afloxan Tablet 300mg
A pain relieving tablet used for joint and muscle pain conditions.
Afloxan Tablet 300mg Uses
- Osteoarthritis and rheumatoid arthritis pain
- Muscle and soft tissue pain
- Painful periods (dysmenorrhea)
- Pain and swelling after minor injury
Afloxan Tablet 300mg Benefits
- Combined pain and inflammation relief in one tablet
- Prodrug form is generally gentler on the stomach than plain indomethacin
- Restored daily movement and function in joint pain conditions
What Experts Say
Proglumetacin is a prodrug that the body converts into indomethacin, a potent nonsteroidal anti-inflammatory that blocks the cyclooxygenase enzymes responsible for producing pain and inflammation signaling molecules called prostaglandins. By lowering prostaglandin levels at the site of injury or joint disease, it reduces pain, swelling, and stiffness.
Doctors often choose proglumetacin over plain indomethacin because the prodrug form is associated with better stomach tolerance while still delivering strong anti-inflammatory activity once converted in the body. It is commonly prescribed for painful joint and muscle conditions where inflammation is a major driver of symptoms.
Musculoskeletal pain, including arthritis and soft tissue injuries, is a frequent reason for clinic visits across Pakistan, and NSAID type tablets like this one remain a mainstay of short term management. Physicians still weigh stomach and cardiovascular risk before prescribing longer courses, particularly in older patients or those with existing heart or kidney disease.
Drug Class
- Nonsteroidal Anti-Inflammatory Drug (NSAID)
- Indomethacin Prodrug
Afloxan Tablet 300mg Uses in Urdu
- اوسٹیوآرتھرائٹس اور رمیٹائیڈ گٹھیا کے درد میں استعمال ہوتا ہے
- پٹھوں اور نرم بافتوں کے درد میں مددگار ہے
- ماہواری کے دردناک ایام میں استعمال کیا جاتا ہے
- چھوٹی چوٹ کے بعد درد اور سوجن کم کرنے کے لیے تجویز کیا جاتا ہے
Afloxan Tablet 300mg formula
How to use Afloxan Tablet 300mg?
- Take the tablet with food or a full glass of water to reduce stomach irritation.
- Swallow the tablet whole, without crushing or chewing it.
- Take at the same times each day as your doctor advises.
- Use the lowest effective dose for the shortest time needed to control symptoms.
- Do not exceed the prescribed dose or duration without medical advice.
Drug Interactions
- Warfarin and Other Blood Thinners: This tablet can increase bleeding risk when combined with anticoagulant medicines.
- Other NSAIDs or Aspirin: Taking another NSAID at the same time raises the risk of stomach ulcers and bleeding.
- ACE Inhibitors and Diuretics: This combination can reduce kidney function and blunt blood pressure control.
- Lithium: This tablet can raise lithium levels in the blood, increasing the risk of toxicity.
Risks and warnings
- Stomach Ulcers: This tablet can irritate the stomach lining and cause ulcers or bleeding, especially with long term use.
- Heart and Stroke Risk: Long term use of NSAID type painkillers can raise the risk of heart attack or stroke.
- Kidney Function: Caution is needed in existing kidney disease, since it can reduce blood flow to the kidneys.
- Aspirin or NSAID Allergy: This tablet should be avoided if you have had an asthma attack or allergic reaction to aspirin or another NSAID.
- Pregnancy: This tablet should be avoided in the last trimester of pregnancy, since it can affect the baby's circulation.
- Bleeding Risk: Caution is needed in people with bleeding disorders or those taking blood thinners.
Afloxan Tablet 300mg Side Effects
- Stomach pain or indigestion
- Nausea
- Heartburn
- Headache or dizziness
- Fluid retention or mild swelling
- Raised blood pressure
- Stomach ulcer or bleeding with prolonged use
Storage Conditions
- Store the tablets at room temperature, below 30°C.
- Keep the strip in its original packaging away from moisture.
- Protect from direct sunlight and heat.
- Keep out of reach of children.
