Afloxan Capsule 150mg

About Afloxan Capsule 150mg

Uses

• Relieves pain and stiffness from osteoarthritis
• Used for rheumatoid arthritis joint pain and swelling
• Eases lower back pain and sciatica
• Helps with pain after sprains, strains and minor injuries
• Used for ankylosing spondylitis related back stiffness
• Reduces pain and swelling from soft tissue rheumatism

Benefits

• Provides longer lasting pain relief with twice daily dosing
• Reduces both pain and inflammation at the same time
• Helps improve joint movement and daily function
• Generally easier on the stomach than some older NSAIDs

What Experts Say

Proglumetacin is a prodrug that the body converts into indomethacin, a well studied anti-inflammatory medicine. Indomethacin blocks enzymes called COX-1 and COX-2, which lowers the chemicals responsible for pain, swelling and fever in the joints. This slow conversion also means the drug tends to act more gently on the stomach lining than plain indomethacin.

Doctors across Pakistan, including Lahore, Karachi, Islamabad and Rawalpindi, commonly prescribe Afloxan for chronic joint conditions such as osteoarthritis, rheumatoid arthritis and ankylosing spondylitis when simpler painkillers no longer control the pain. It is usually given for a short, defined course rather than continuous long term use, and the dose is adjusted based on how well the pain responds.

People with a history of stomach ulcers, heart disease or kidney problems need close monitoring, since NSAIDs can affect all three organs. Older adults are more sensitive to side effects and often need a lower starting dose. Long term use should always be reviewed by a doctor.

Drug Class

• Non-steroidal anti-inflammatory drug (NSAID)

Afloxan Capsule 150mg formula

• Proglumetacin

Available forms

• Capsule

How to use Afloxan Capsule 150mg?

• Take one capsule in the morning and one in the evening, or as directed by your doctor
• Swallow the capsule whole with a full glass of water
• Take after meals to reduce the chance of stomach upset
• Do not crush or open the capsule before swallowing
• Use the lowest effective dose for the shortest time needed to control symptoms

Drug Interactions

• Blood Thinners: Increases the risk of bleeding when taken with warfarin or other anticoagulants
• Aspirin: Combining with aspirin raises the risk of stomach irritation and bleeding
• Blood Pressure Medicines: Can reduce the effectiveness of ACE inhibitors and diuretics
• Corticosteroids: Taking together increases the risk of stomach ulcers

Risks and warnings

• Stomach Ulcers: Avoid use if you have active stomach ulcers or a history of gastrointestinal bleeding
• Heart Disease: Long term NSAID use can raise the risk of heart attack and stroke in people with existing heart conditions
• Kidney Disease: Use with caution in kidney disease, since NSAIDs can reduce kidney function further
• Pregnancy And Breastfeeding: Avoid during the third trimester of pregnancy and use only if clearly needed while breastfeeding
• Alcohol: Avoid regular alcohol use, since it raises the risk of stomach bleeding with this medicine

Afloxan Capsule Side Effects

• Stomach pain or indigestion
• Nausea
• Heartburn
• Headache
• Dizziness
• Diarrhea or constipation
• Fluid retention with mild swelling in the feet
• Stomach ulcers or gastrointestinal bleeding (rare)
• Allergic skin reactions (rare)
• Raised blood pressure with long term use (rare)

Storage Conditions

• Store below 30°C in a cool, dry place
• Keep the capsules in their original blister pack until use
• Protect from moisture and direct sunlight
• Keep out of reach of children