Artifen Injection 75mg/3ml

About Artifen Injection 75mg/3ml

Artifen Injection 75mg/3ml Uses

• Moderate to severe pain and inflammation from arthritis, spondylitis, or musculoskeletal injuries
• Postoperative and post traumatic pain
• Acute gouty arthritis
• Renal colic and pain from gallbladder conditions
• Severe menstrual cramps (dysmenorrhea)
• Soft tissue injuries, sprains, and ligament strains

Artifen Injection 75mg/3ml Benefits

• Provides faster pain relief than oral tablets since it bypasses the digestive system
• Useful for patients who cannot swallow tablets or are vomiting
• Strong anti-inflammatory action for acute flare ups
• Given under medical supervision, reducing dosing errors
• Effective for short term control of severe pain not responding to oral analgesics

What Experts Say

Diclofenac sodium works by blocking cyclooxygenase (COX-1 and COX-2) enzymes, which lowers the production of prostaglandins responsible for pain, swelling, and fever. Physicians prefer the injectable form when a patient needs faster and more reliable pain control than an oral tablet can offer, since intramuscular absorption reaches peak plasma levels within minutes rather than hours.

In acute settings such as post surgical pain, renal colic, or a severe gout flare, doctors often start with this injection for one to two days before switching the patient to oral diclofenac or another NSAID. This short injectable course limits total drug exposure while still controlling pain quickly during the most painful phase of an illness or recovery.

Because prostaglandins also protect the stomach lining, support kidney blood flow, and influence clotting, doctors weigh the GI, renal, and cardiovascular risks before prescribing. Patients with ulcer history, kidney disease, heart disease, or uncontrolled blood pressure are monitored closely or offered an alternative, and doctors generally avoid using diclofenac injections for more than a few days at a time.

Drug Class

• Non-Steroidal Anti-Inflammatory Drug (NSAID)
• Phenylacetic acid derivative

Artifen Injection 75mg/3ml formula

• Diclofenac Sodium

Available forms

• Injection

How to use Artifen Injection 75mg/3ml?

• Administer by deep intramuscular injection into the upper outer gluteal muscle
• Usual adult dose is 75mg once daily, increased to 75mg twice daily in severe cases
• Do not exceed 150mg in 24 hours
• Limit use to 1 to 2 days, then switch to oral diclofenac if further treatment is needed
• Must be given by a doctor or trained healthcare professional, not for self injection
• Do not inject into the same site repeatedly
• Not for intravenous use

Drug Interactions

• Anticoagulants (Warfarin): Increases the risk of serious bleeding
• Other NSAIDs and Aspirin: Raises the risk of stomach ulcers and bleeding, and can reduce the heart protective effect of low dose aspirin
• ACE Inhibitors and ARBs: Can reduce their blood pressure lowering effect and raise the risk of kidney injury
• Lithium: Can raise lithium levels in the blood and cause toxicity
• Methotrexate: Can increase methotrexate levels and toxicity risk
• Diuretics: May reduce their effectiveness and increase the risk of kidney problems

Risks and warnings

• GI Bleeding Risk: Can cause stomach ulcers, bleeding, or perforation, especially with long term or high dose use
• Cardiovascular Risk: May increase the risk of heart attack or stroke, particularly with prolonged use or existing heart disease
• Renal Impairment: Can reduce blood flow to the kidneys and worsen kidney function, especially in dehydrated or elderly patients
• Injection Site Reaction: May cause pain, swelling, redness, or rarely tissue damage at the injection site
• Pregnancy Risk: Should be avoided in the third trimester due to risk of premature closure of a fetal blood vessel
• Hepatic Risk: Can raise liver enzymes and should be used cautiously in patients with liver disease

Artifen Injection 75mg/3ml Side Effects

• Pain, redness, or swelling at the injection site
• Nausea and vomiting
• Stomach pain or heartburn
• Headache and dizziness
• Diarrhea or constipation
• Drowsiness
• Skin rash or itching
• Fluid retention or swelling in the legs
• Ringing in the ears (tinnitus)
• Raised liver enzymes

Storage Conditions

• Store below 25°C, away from direct heat and sunlight
• Keep the ampoules in their original box until ready to use
• Do not freeze
• Keep out of reach and sight of children
• Discard the ampoule if the solution looks cloudy or contains particles
• Use the ampoule immediately after opening and discard any unused solution