About Axalor Tablet 10mg
Axalor Tablet 10mg is a Loratadine based antihistamine used to relieve allergy symptoms.
Axalor Tablet 10mg Uses
- Seasonal allergic rhinitis with sneezing and runny nose
- Perennial allergic rhinitis symptoms year round
- Chronic idiopathic urticaria and hives
- Itchy, watery eyes caused by allergies
- Skin itching linked to allergic reactions
Axalor Tablet 10mg Benefits
- Provides 24 hour allergy relief with one daily dose
- Causes less drowsiness than older antihistamines
- Works quickly to control sneezing and nasal congestion
- Safe for long term daily use in chronic allergy cases
- Does not commonly interfere with daily work or study routines
What Experts Say
Loratadine works by selectively blocking peripheral H1 histamine receptors, which reduces sneezing, itching, and nasal congestion without significantly crossing the blood brain barrier. This selective action explains why the drug produces less sedation compared to first generation antihistamines like chlorpheniramine.
Clinical pharmacology studies confirm that loratadine reaches peak plasma concentration within one to two hours and maintains therapeutic antihistamine activity for over 24 hours, supporting once daily dosing. The liver converts loratadine into descarboethoxyloratadine, an active metabolite that extends its duration of action.
Because loratadine carries minimal anticholinergic and sedative properties, experts consider it a preferred option for patients who need daily allergy control without cognitive impairment. Dose adjustment is generally advised in patients with significant liver impairment since drug metabolism slows considerably in that population.
Drug Class
- Second Generation Antihistamine (H1 Receptor Blocker)
Axalor Tablet 10mg Uses in Urdu
- موسمی الرجی جیسے چھینکیں اور ناک بہنا
- سارا سال رہنے والی الرجک ناک کی سوزش
- جلد پر خارش اور چھپاکی (Urticaria)
- آنکھوں میں خارش اور پانی آنا
- الرجی کی وجہ سے جلد پر خارش
Axalor Tablet 10mg formula
How to use Axalor Tablet 10mg?
- Take one tablet by mouth once daily
- Swallow the tablet whole with a glass of water
- Take with or without food as preferred
- Use at the same time each day for consistent relief
- Do not exceed one tablet in a 24 hour period
- Consult a doctor before giving to children under 12 years
Drug Interactions
- Ketoconazole: Raises loratadine plasma levels by inhibiting the liver enzymes that break it down.
- Erythromycin: Increases loratadine blood concentration through the same metabolic inhibition pathway.
- Cimetidine: Slows loratadine breakdown in the liver, leading to higher drug levels in the body.
- Alcohol: May add to mild drowsiness in sensitive individuals, though loratadine itself is largely non-sedating.
- Other CNS Depressants: Combined use may slightly increase the chance of tiredness or reduced alertness.
Risks and warnings
- Liver Disease: Patients with significant liver impairment may need a lower dose since drug clearance slows considerably.
- Kidney Disease: Reduced dosing frequency may be required in patients with severe kidney impairment.
- Pregnancy: Use only if clearly needed and after discussing risks and benefits with a doctor.
- Breastfeeding: Small amounts pass into breast milk, so medical advice is recommended before use.
- Elderly Patients: Older adults may be more sensitive to mild drowsiness and should start with caution.
- Driving Or Operating Machinery: Rare drowsiness can occur, so caution is advised until individual response is known.
Axalor Tablet 10mg Side Effects
- Headache
- Dry mouth
- Fatigue or tiredness
- Mild drowsiness in some patients
- Nausea
- Stomach discomfort
- Nervousness or restlessness
Storage Conditions
- Store below 30 degrees Celsius in a cool, dry place
- Protect the tablets from direct sunlight and moisture
- Keep the strip in its original packaging until use
- Keep out of reach of children
- Discard tablets after the printed expiry date
