Axifen Tablet 100mg

About Axifen Tablet 100mg

Axifen Tablet 100mg Uses

• Osteoarthritis pain and stiffness
• Rheumatoid arthritis
• Ankylosing spondylitis
• Acute gout attacks
• Post operative and post traumatic pain
• Muscular and skeletal pain
• Toothache and dental pain
• Menstrual pain

Axifen Tablet 100mg Benefits

• Reduces joint pain and swelling in arthritis
• Eases acute muscle and back pain
• Lowers fever linked to inflammatory conditions
• Once or twice daily sustained release dosing improves compliance
• Provides longer lasting relief than short acting diclofenac tablets

What Experts Say

Diclofenac sodium is a phenylacetic acid derivative NSAID that blocks cyclooxygenase 1 and 2 enzymes, cutting prostaglandin production at the site of injury. This lowers pain signaling, swelling, and local tissue heat within a few hours of dosing. It is one of the more potent NSAIDs used for moderate to severe inflammatory pain.

The sustained release formulation in Axifen Tablet 100mg releases the drug slowly over several hours, which keeps blood levels steadier and reduces the number of daily doses needed for chronic joint conditions like osteoarthritis and rheumatoid arthritis. This steadier release also helps limit sharp peaks in drug concentration that can worsen stomach irritation.

Clinicians weigh its strong anti-inflammatory effect against known NSAID risks, particularly gastrointestinal irritation and cardiovascular strain with prolonged use. Short term use at the lowest effective dose is generally recommended, and patients with heart, kidney, or stomach conditions need closer monitoring before starting therapy.

Drug Class

• Non Steroidal Anti Inflammatory Drug (NSAID)
• Phenylacetic acid derivative
• Cyclooxygenase (COX 1 and COX 2) inhibitor

Axifen Tablet 100mg formula

• Diclofenac Sodium

Available forms

• Tablet

How to use Axifen Tablet 100mg?

• Swallow the tablet whole with a full glass of water
• Do not crush, chew, or split the sustained release tablet
• Take with food or milk to lower stomach irritation
• Use the lowest effective dose for the shortest time needed
• Take at the same time each day for consistent blood levels
• Follow the exact dose and duration advised by the prescribing doctor

Drug Interactions

• Aspirin and Other NSAIDs: Combined use raises the risk of stomach ulcers and bleeding.
• Warfarin and Blood Thinners: Diclofenac can increase bleeding risk when taken with anticoagulants.
• ACE Inhibitors and ARBs: May reduce the blood pressure lowering effect and strain kidney function.
• Diuretics: Diclofenac can lower the effectiveness of water pills and add kidney stress.
• Lithium: Blood lithium levels can rise to unsafe levels when combined with diclofenac.
• Methotrexate: Diclofenac can raise methotrexate levels, increasing toxicity risk.
• Corticosteroids: Combined use further increases the risk of gastrointestinal ulcers.

Risks and warnings

• Gastrointestinal Bleeding: Can cause stomach ulcers, bleeding, or perforation, especially with long term use.
• Cardiovascular Risk: May raise the risk of heart attack or stroke, particularly with high doses or prolonged use.
• Kidney Impairment: Can reduce kidney function, especially in dehydrated patients or those with existing kidney disease.
• Pregnancy: Should be avoided in the third trimester due to risk of harm to the unborn baby.
• Liver Function: May elevate liver enzymes and should be used cautiously in patients with liver disease.
• Asthma and Allergy: Can trigger bronchospasm or allergic reactions in patients sensitive to NSAIDs or aspirin.

Axifen Tablet 100mg Side Effects

• Stomach pain and indigestion
• Nausea and vomiting
• Diarrhea or constipation
• Headache and dizziness
• Skin rash or itching
• Fluid retention and swelling in the legs
• Raised blood pressure
• Stomach ulcer or gastrointestinal bleeding
• Liver enzyme elevation
• Kidney function changes

Storage Conditions

• Store below 30 degrees Celsius in a cool, dry place
• Keep the tablets in the original blister pack until use
• Protect from direct sunlight and moisture
• Keep out of reach of children
• Do not use beyond the printed expiry date