About Bezel Tablet 500 mcg
Bezel Tablet 500 mcg is a mecobalamin vitamin B12 supplement for nerve repair and B12 deficiency anaemia.
Bezel Tablet 500 mcg Uses
- Treatment of vitamin B12 deficiency in adults and elderly patients
- Management of peripheral neuropathy with numbness, tingling or burning feet
- Supportive care in diabetic nerve pain when vitamin B12 levels are low
- Correction of megaloblastic anaemia caused by low vitamin B12
- Adjunct treatment in pernicious anaemia alongside the doctor advised plan
- Nerve support during long term metformin or acid suppressing therapy
Bezel Tablet 500 mcg Benefits
- Provides the active coenzyme form of vitamin B12 that cells can use directly
- Helps rebuild the myelin sheath that protects nerve fibres
- Supports normal red blood cell production and eases deficiency related fatigue
- Offers an oral option for patients who want to avoid repeated injections
- Generally well tolerated during long courses taken under medical supervision
- Useful for vegetarian eating patterns that supply very little vitamin B12
What Experts Say
Mecobalamin is the coenzyme form of vitamin B12, so it works inside nerve and bone marrow cells without the extra conversion step that cyanocobalamin requires. Physicians usually prefer it when the clinical picture is dominated by numbness, burning feet or tingling hands rather than anaemia alone.
Doctors across Pakistan see a heavy burden of vitamin B12 deficiency linked to low animal protein intake, long term metformin use in diabetes and frequent use of acid suppressing medicines. A 500 mcg oral dose is absorbed partly by passive diffusion, which is why tablets still help many patients whose intrinsic factor activity is limited.
Response is judged on both symptoms and laboratory values. Serum vitamin B12, complete blood count and reticulocyte response are rechecked after a few weeks, and folate is measured at the same time because correcting B12 alone can hide a folate problem. Nerve symptoms settle slowly over weeks to months, so a course is usually continued for at least three months before any change is considered.
Drug Class
- Vitamin B12 analogue
- Haematinic vitamin supplement
- Neurotropic vitamin
Bezel Tablet 500 mcg Uses in Urdu
- وٹامن بی 12 کی کمی کے علاج کے لیے استعمال ہوتی ہے
- ہاتھوں اور پیروں کے سن ہونے اور جھنجھناہٹ میں آرام دیتی ہے
- ذیابیطس کے مریضوں میں اعصابی درد اور جلن کم کرنے میں مددگار ہے
- وٹامن بی 12 کی کمی سے ہونے والی خون کی کمی دور کرتی ہے
- اعصاب کی مرمت اور جسمانی کمزوری میں بہتری کے لیے دی جاتی ہے
Bezel Tablet 500 mcg formula
How to use Bezel Tablet 500 mcg?
- Take Bezel Tablet 500 mcg exactly as your doctor or pharmacist advises.
- The usual adult dose is one tablet up to three times a day, or as prescribed.
- Swallow the tablet whole with a glass of water, with or without food.
- Try to take your doses at the same times each day to keep levels steady.
- If you miss a dose, take it when you remember unless the next dose is close.
- Never double a dose to make up for a missed one.
- Continue the full course even if tingling and fatigue start improving early.
Drug Interactions
- Metformin: Long term use lowers vitamin B12 absorption, so levels should be monitored and supplementation may be needed.
- Proton pump inhibitors and H2 blockers: Reduced stomach acid limits vitamin B12 release from food and can deepen deficiency.
- Colchicine: Interferes with vitamin B12 absorption in the small intestine and can blunt the response to treatment.
- Chloramphenicol: May reduce the bone marrow response to vitamin B12 in patients being treated for anaemia.
- Aminosalicylic acid: Can decrease vitamin B12 uptake from the gut during prolonged therapy.
- Alcohol: Heavy regular intake damages absorption and worsens both nerve symptoms and anaemia.
Risks and warnings
- Undiagnosed anaemia: Vitamin B12 can improve blood counts while an underlying folate deficiency or nerve problem continues untreated.
- Pernicious anaemia: Patients who cannot absorb vitamin B12 from the gut may need injections instead of tablets, so follow the doctor advised route.
- Allergy: Stop the tablet and seek help if rash, itching, swelling of the face or breathing difficulty develops.
- Leber hereditary optic neuropathy: Cobalamin products can worsen this rare eye condition, so tell your doctor about any inherited vision disorder.
- Pregnancy and breastfeeding: Use only on medical advice, even though vitamin B12 is generally considered safe in normal doses.
- Occupational exposure: Prolonged handling of mercury or heavy metals may affect vitamin B12 status, so mention such work to your doctor.
- Kidney disease: Dose adjustment may be considered in significant renal impairment, so share your full medical history.
- Self medication: Persistent numbness, weakness or severe tiredness needs proper testing rather than long term unsupervised supplement use.
Bezel Tablet 500 mcg Side Effects
- Nausea
- Loss of appetite
- Mild stomach upset
- Diarrhoea
- Headache
- Dizziness
- Skin rash or itching
- Flushing or a warm feeling
- Excessive sweating
- Feeling unusually tired at the start of treatment
- Rare allergic reaction with facial swelling or difficulty breathing
- Rare acne like eruptions with prolonged high dose use
Storage Conditions
- Store the blister strips below 30 degrees Celsius in a dry place.
- Keep the tablets in their original foil until the moment you take a dose, since moisture damages them.
- Protect the pack from direct sunlight and avoid humid places such as bathroom shelves.
- Keep the carton out of reach of children.
- Do not use any tablet from a torn strip or after the printed expiry date.
