Bofalgan Injection 100ml

About Bofalgan Injection 100ml

Bofalgan Injection 100ml Uses

• Moderate to severe pain after surgery, when oral pain relief is not possible
• High grade fever in hospitalized patients who cannot take medicines by mouth
• Short term pain control after orthopedic, general surgical, or gynecological procedures
• Fever and pain management in ICU and emergency department settings

Bofalgan Injection 100ml Benefits

• Fast onset, with pain relief starting within 5 to 10 minutes and fever control within about 30 minutes
• A useful option for patients who are nauseous, vomiting, or not allowed anything by mouth after surgery
• A non-opioid choice for short term post operative pain, with lower dependency risk than opioid injections
• Fewer oral medicines needed during a hospital stay, since the drug works directly through the vein

What Experts Say

Doctors in major hospitals across Pakistan use IV paracetamol infusions like Bofalgan as part of standard post operative pain protocols. It is often the first choice for pain relief after major surgery, before stronger opioid medicines are considered.

Anesthesiologists often combine it with other non-opioid painkillers to reduce the total opioid dose a patient needs, a practice known as multimodal pain management.

Liver function checks are a routine part of care before repeated dosing, especially in patients with a history of hepatitis or alcohol use.

Drug Class

• Analgesic and Antipyretic (Non-opioid, Paracetamol group)

Bofalgan Injection 100ml formula

• Paracetamol

Available forms

• IV Infusion (100ml)

How to use Bofalgan Injection 100ml?

• This is a hospital administered injection, never given at home by patients themselves
• A doctor or trained nurse gives it as a slow intravenous infusion over about 15 minutes, using the full 100ml bottle or bag
• The usual adult dose is one 1g/100ml infusion, repeated every 4 to 6 hours as directed by the treating doctor
• A maximum of 4 grams, or four infusions, is allowed in 24 hours for an average adult
• Patients with liver or kidney problems usually need a lower dose and a longer gap between doses
• The IV line is flushed before and after the infusion so it does not mix with other injectable medicines

Drug Interactions

• Warfarin and other blood thinners: Regular use of paracetamol infusion can increase the blood thinning effect, raising bleeding risk.
• Alcohol: Chronic alcohol use increases the risk of liver toxicity when combined with paracetamol.
• Other paracetamol containing medicines: Extra paracetamol tablets, syrups, or infusions taken at the same time can lead to accidental overdose.
• Liver enzyme inducing drugs such as phenytoin, carbamazepine, or rifampicin: These can raise the risk of liver toxicity from paracetamol.
• Chloramphenicol: Paracetamol may prolong the effect of chloramphenicol in the body.

Risks and warnings

• Liver toxicity: High doses or repeated dosing above the recommended limit can cause serious, sometimes fatal liver damage.
• Hepatic impairment: Patients with active liver disease or chronic alcohol use need lower doses and closer monitoring.
• Severe hepatic impairment: This injection should not be given to patients with severe liver failure.
• Low body weight: Patients under 50kg need weight based dosing to avoid accidental overdose.
• Dehydration or malnutrition: Chronic malnutrition, severe dehydration, or low glutathione stores raise the risk of liver injury.
• Kidney impairment: A longer gap between doses is usually needed in patients with reduced kidney function.
• Newborns: This injection is not recommended for premature or newborn infants without specialist supervision.

Bofalgan Injection 100ml Side Effects

Common Side Effects

• Nausea
• Vomiting
• Headache
• Pain or redness at the infusion site
• Mild drop in blood pressure during the infusion

Serious Side Effects

• Signs of liver damage such as yellowing of skin or eyes, dark urine, or unusual tiredness
• Severe allergic reaction with swelling of the face, lips, or throat
• Difficulty breathing
• Severe skin reaction with blistering or peeling

Storage Conditions

• Storage temperature should stay below 30°C, away from direct sunlight and heat
• The infusion bottle should never be frozen
• Original carton packaging protects the solution from light until it is ready for use
• A quick visual check before use is important; the solution should not be used if it looks cloudy, discolored, or has visible particles
• Each bottle is for single use only, and any leftover solution after opening should be discarded
• Hospital pharmacy or clinical storage areas are the right place for this product, not home medicine cabinets