Covance Tablet 5 / 80mg

About Covance Tablet 5 / 80mg

Covance Tablet Uses

• High blood pressure (hypertension) treatment in adults.
• A common addition when blood pressure is not controlled by a single medicine alone.
• Long term risk reduction for heart attack and stroke linked to uncontrolled hypertension.

Covance Tablet Benefits

• Two blood pressure lowering mechanisms combined in a single tablet for better control.
• Fewer pills needed compared to taking each medicine separately.
• Long term protection for the heart and kidneys from high blood pressure damage.

What Experts Say

Pakistani physicians commonly prescribe Amlodipine and Valsartan together when a single blood pressure medicine fails to bring readings under control. Amlodipine relaxes blood vessel walls by blocking calcium channels, while Valsartan blocks angiotensin II, a hormone that narrows blood vessels. Both mechanisms together often give steadier control than a higher dose of one drug alone.

Hypertension is extremely common across Pakistan, and many patients only get diagnosed after years of silent high readings. A fixed dose combination like this one is often favored by doctors in Pakistan because it improves how consistently patients actually take their medicine. Fewer tablets to remember each day generally means better long term blood pressure control and fewer missed doses.

Kidney function and blood potassium levels are usually checked before this combination is started, since Valsartan can affect both. Regular follow up visits allow the dose to be adjusted safely. Ankle swelling or unusual dizziness should be reported promptly so the treatment plan can be reviewed.

Drug Class

• Calcium Channel Blocker (Amlodipine)
• Angiotensin II Receptor Blocker / ARB (Valsartan)
• Antihypertensive Combination Therapy

Covance Tablet 5 / 80mg formula

• Amlodipine 5mg + Valsartan 80mg

Available forms

• Tablet

How to use Covance Tablet 5 / 80mg?

• One tablet daily, with or without food, at a consistent time each day, is the usual adult dose.
• A full glass of water is recommended when swallowing the tablet whole.
• Sudden discontinuation without medical advice is not recommended.
• Missed doses can be taken as soon as remembered, unless the next dose is nearly due.

Drug Interactions

• Potassium Sparing Diuretics: Combined use can raise blood potassium to unsafe levels.
• NSAIDs: Regular use of painkillers like Ibuprofen or Diclofenac can reduce the blood pressure lowering effect.
• Simvastatin: Amlodipine can raise Simvastatin levels, increasing the risk of muscle related side effects.
• Lithium: Valsartan can raise Lithium levels in the blood, requiring closer monitoring.
• Other Blood Pressure Medicines: Additional antihypertensives combined with this medicine can cause blood pressure to drop too low.

Risks and warnings

• Low Blood Pressure: Dizziness or fainting is possible, especially when standing up quickly.
• Kidney Function: Regular monitoring is important in patients with kidney disease, since Valsartan affects renal blood flow.
• Pregnancy: This medicine is not recommended during pregnancy, especially in the second and third trimester.
• Swelling: Ankle or leg swelling is a known effect of Amlodipine in some patients.
• Potassium Levels: Blood potassium can rise on this medicine, so periodic blood tests are advised for at-risk patients.

Covance Tablet Side Effects

• Headache
• Dizziness
• Swelling in the ankles or feet
• Fatigue
• Flushing or warmth in the face
• Low blood pressure symptoms such as lightheadedness
• Nausea
• Back pain
• Cough
• Elevated potassium levels on blood tests

Storage Conditions

• Store below 30°C in a cool, dry place away from direct sunlight.
• Keep the blister strip inside its original carton until the dose is due.
• Keep out of reach of children.
• Avoid storing in the bathroom or near a kitchen sink where moisture can reach the tablets.