Listan-AM Tablet 5mg/80mg

About Listan-AM Tablet 5mg/80mg

Listan-AM Tablet Uses

• Treats high blood pressure that has not responded well enough to a single medicine.
• Manages chronic stable angina by improving blood flow to the heart muscle.
• Used in patients who need both a calcium channel blocker and an ARB for blood pressure control.
• Helps reduce the frequency of chest pain episodes linked to narrowed coronary arteries.
• Supports long-term cardiovascular risk reduction in patients with resistant hypertension.

Listan-AM Tablet Benefits

• Combines two different blood pressure lowering mechanisms in a single daily tablet.
• Amlodipine relaxes blood vessel walls, while valsartan blocks a hormone that raises blood pressure.
• Reduces pill burden for patients who would otherwise need two separate prescriptions.
• Suitable for patients whose blood pressure remains high on amlodipine or valsartan alone.

What Experts Say

Cardiologists in Pakistan often move patients to a combination like Listan-AM when blood pressure stays high despite one medicine at a full dose. Amlodipine widens blood vessels by blocking calcium entry into muscle cells, while valsartan blocks a separate hormone pathway, so the two drugs lower blood pressure through different routes rather than doubling the same effect.

This dual mechanism is useful in a population where hypertension is often diagnosed late and already resistant to single-drug treatment. Physicians note that combining a calcium channel blocker with an ARB also tends to cause less ankle swelling than amlodipine alone, since valsartan can offset some of that fluid shift.

Doctors still recommend regular blood pressure checks and kidney function tests while on this combination, especially in older adults or those with existing heart disease. Missing doses or stopping suddenly can cause blood pressure to rebound, so consistent daily use matters more than with some other heart medicines.

Drug Class

• Calcium Channel Blocker and Angiotensin Receptor Blocker Combination

Listan-AM Tablet 5mg/80mg formula

• Amlodipine 5mg + Valsartan 80mg

Available forms

• Tablet

How to use Listan-AM Tablet 5mg/80mg?

• Take one tablet of Listan-AM 5mg/80mg once daily, with or without food.
• Take it at the same time every day for the most consistent blood pressure control.
• Swallow the tablet whole with a glass of water.
• Do not stop taking it suddenly without consulting your doctor first.
• If a dose is missed, take it as soon as remembered unless the next dose is nearly due.

Drug Interactions

• Simvastatin: Amlodipine can raise simvastatin levels, increasing the risk of muscle problems.
• Potassium supplements: Can raise blood potassium to unsafe levels when combined with valsartan.
• Other blood pressure medicines: Using more than one antihypertensive together raises the risk of excessive blood pressure drops.
• NSAIDs: Regular use can reduce the blood pressure lowering effect of valsartan.
• Grapefruit juice: Can increase amlodipine levels in the blood, raising side effect risk.

Risks and warnings

• Pregnancy: Not recommended during pregnancy, as valsartan can cause serious harm to the unborn baby.
• Low blood pressure: Can cause dizziness or fainting, especially when starting treatment or increasing the dose.
• Liver impairment: Requires caution and possible dose adjustment in patients with liver disease.
• Ankle swelling: Amlodipine can cause swelling in the feet and ankles in some patients.
• Heart conditions: Use with caution in patients with severe aortic stenosis or unstable angina.

Listan-AM Tablet Side Effects

• Swelling in the ankles or feet
• Dizziness
• Headache
• Flushing or warmth in the face
• Fatigue
• Low blood pressure
• Palpitations
• Nausea

Storage Conditions

• Store below 30°C in a dry place, away from direct sunlight and moisture.
• Keep the tablets in their original blister strip until you are ready to take them.
• Keep out of reach of children.
• Do not use the tablets after the expiry date printed on the pack.