About Diajard-M Tablet 12.5mg / 1000mg
An empagliflozin and metformin combination tablet used to manage type 2 diabetes in adults.
Diajard-M Tablet Uses
- Diajard-M Tablet controls high blood sugar levels in adults with type 2 diabetes mellitus.
- It supports blood sugar management alongside diet and exercise when metformin alone is not enough.
- Doctors prescribe it to reduce the risk of major cardiovascular events in adults with type 2 diabetes and established heart disease.
- It helps patients who need a higher dose of metformin combined with an SGLT2 inhibitor for better glycemic control.
Diajard-M Tablet Benefits
- Combines two complementary mechanisms in a single tablet for tighter blood sugar control.
- Lowers the risk of heart attack, stroke, and cardiovascular death in high risk diabetic adults.
- Supports modest weight reduction compared to some other diabetes medicines.
- Reduces the pill burden for patients who would otherwise take two separate tablets.
What Experts Say
Empagliflozin is an SGLT2 inhibitor. It blocks glucose reabsorption in the kidney tubules so excess sugar leaves the body through urine instead of staying in the blood. This action works independently of insulin, which makes it useful even as the pancreas produces less insulin over time. It does not typically trigger low blood sugar on its own.
Metformin works differently. It lowers glucose production in the liver and improves how muscle and fat tissue respond to insulin. At the 1000mg strength it delivers a stronger glucose lowering effect for patients who need more than a starting dose. Pairing it with empagliflozin targets liver output and kidney reabsorption together.
Trial data on empagliflozin show a measurable drop in cardiovascular death and heart failure hospitalization among adults with type 2 diabetes and existing heart disease. Metformin remains first line therapy in most diabetes guidelines due to its long safety record. Kidney function is checked periodically since both drugs depend on renal clearance.
Drug Class
- SGLT2 Inhibitor (Empagliflozin)
- Biguanide (Metformin)
Diajard-M Tablet 12.5mg / 1000mg Uses in Urdu
- یہ دوا ٹائپ 2 ذیابیطس کے مریضوں میں بلڈ شوگر کو کنٹرول کرنے کے لیے استعمال ہوتی ہے۔
- یہ ان مریضوں کے لیے تجویز کی جاتی ہے جن کا شوگر لیول اکیلے میٹفارمن سے قابو میں نہیں آتا۔
- یہ دل کے امراض کے خطرے کو کم کرنے میں مدد دیتی ہے، خاص طور پر ان مریضوں میں جنہیں پہلے سے دل کی بیماری ہو۔
- یہ خوراک اور ورزش کے ساتھ مل کر شوگر کے بہتر کنٹرول میں مدد دیتی ہے۔
Diajard-M Tablet 12.5mg / 1000mg formula
- Empagliflozin + Metformin Hydrochloride
How to use Diajard-M Tablet 12.5mg / 1000mg?
- Take one tablet by mouth once daily in the morning with or without food.
- Swallow the tablet whole with a glass of water, do not crush or chew it.
- Take it at the same time each day to maintain steady blood sugar control.
- Continue your prescribed diet and exercise plan alongside this medicine.
- Do not change the dose without your doctor's advice, even if your sugar readings improve.
Drug Interactions
- Insulin And Sulfonylureas: Combining these with Diajard-M raises the risk of low blood sugar, dose adjustment may be needed.
- Diuretics: Water pills combined with this medicine can increase the risk of dehydration and low blood pressure.
- Contrast Dye: Iodinated contrast agents used in imaging scans raise the risk of kidney injury when combined with metformin.
- Alcohol: Heavy alcohol use increases the risk of lactic acidosis and low blood sugar with this medicine.
- Corticosteroids: Steroid medicines can raise blood sugar and reduce the effectiveness of this combination.
Risks and warnings
- Kidney Function: This medicine is not recommended in patients with significantly reduced kidney function, since both ingredients depend on renal clearance.
- Dehydration: Empagliflozin increases urination and can lower blood pressure or cause dehydration, especially in hot weather or with low fluid intake.
- Ketoacidosis: Rare cases of diabetic ketoacidosis with near normal blood sugar have been reported with SGLT2 inhibitors, seek care for unusual nausea, vomiting, or breathing difficulty.
- Lactic Acidosis: Metformin carries a rare but serious risk of lactic acidosis, particularly in patients with kidney or liver impairment.
- Genital Infections: Increased urinary glucose can raise the risk of yeast and urinary tract infections.
- Surgery: Your doctor may pause this medicine before major surgery or contrast dye procedures.
Diajard-M Tablet Side Effects
- Urinary tract infection
- Genital yeast infection
- Increased urination
- Nausea or upset stomach
- Diarrhea
- Low blood sugar when combined with insulin or sulfonylureas
- Dizziness or lightheadedness
- Dehydration
- Rare risk of diabetic ketoacidosis
- Rare risk of lactic acidosis
Storage Conditions
- Store below 30 degrees Celsius in a cool, dry place.
- Keep the tablets in their original blister pack until use.
- Protect from moisture and direct sunlight.
- Keep out of reach of children.
