Diamicron MR Tablet 30mg

About Diamicron MR Tablet 30mg

Diamicron MR Tablet 30mg Uses

• Type 2 diabetes mellitus, especially as a starting dose
• Initial blood sugar control in newly diagnosed adults
• Dose titration step before moving to a higher Gliclazide MR strength
• Combination therapy with Metformin or other antidiabetic medicines

Diamicron MR Tablet 30mg Benefits

• Gentler starting dose that lowers the risk of early hypoglycemia
• Suitable for elderly patients or those with mild kidney impairment who need cautious dosing
• Once daily modified release action even at the lower strength
• Allows gradual dose adjustment based on blood sugar response

What Experts Say

Gliclazide is a second generation sulfonylurea that lowers blood glucose by stimulating insulin release from pancreatic beta cells. It closes ATP sensitive potassium channels on the cell membrane, which triggers calcium entry and insulin secretion in response to circulating glucose levels.

Doctors commonly start therapy at the 30mg modified release strength, particularly in elderly patients, those with mild kidney or liver impairment, or anyone new to sulfonylurea treatment. Starting low reduces the chance of early hypoglycemia while the body adjusts to the medicine's insulin releasing action.

Dose increases usually happen gradually, at intervals of at least one month, based on fasting blood glucose and HbA1c results, up to a maximum of 120mg once daily. This titration approach lets physicians find the lowest effective dose for each patient rather than starting at a higher strength that may cause unnecessary blood sugar drops.

Drug Class

• Second Generation Sulfonylurea, Antidiabetic

Diamicron MR Tablet 30mg formula

• Gliclazide

Available forms

• Tablet

How to use Diamicron MR Tablet 30mg?

• Take one tablet by mouth once daily with breakfast, usually as a starting dose
• Swallow the tablet whole with a glass of water, do not crush or chew
• Your doctor may increase the dose gradually based on blood sugar readings
• Do not change the dose on your own without medical advice
• Do not skip breakfast after taking this tablet to avoid low blood sugar

Drug Interactions

• Miconazole, oral or gel form, is contraindicated due to severe hypoglycemia risk
• Other antidiabetic medicines can increase the risk of low blood sugar
• NSAIDs such as ibuprofen can enhance the blood sugar lowering effect
• Alcohol increases the risk of hypoglycemia
• Beta blockers may mask the warning signs of low blood sugar
• Corticosteroids can raise blood sugar and reduce effectiveness
• Warfarin and other anticoagulants may have an enhanced effect when combined
• Danazol raises blood sugar and is generally avoided with Gliclazide

Risks and warnings

• Can cause hypoglycemia, especially if a meal is skipped or delayed
• Not suitable for type 1 diabetes or diabetic ketoacidosis
• Use with caution in elderly patients and those with kidney or liver impairment
• Avoid during pregnancy and breastfeeding unless a doctor advises otherwise
• Use caution when driving or operating machinery due to hypoglycemia risk
• Use with caution in patients with G6PD deficiency
• Tablet must be swallowed whole, never crushed or chewed

Diamicron MR Tablet 30mg Side Effects

• Low blood sugar, symptoms include sweating, shakiness and confusion
• Nausea and mild abdominal pain
• Diarrhea or constipation
• Skin rash or itching
• Mild weight gain
• Dizziness or headache
• Temporary blurred vision when starting treatment
• Rare changes in liver enzyme levels
• Rare reductions in blood cell counts

Storage Conditions

• Store below 30°C in a cool, dry place away from direct sunlight
• Keep the tablet in its original blister strip until it is time to take it
• Keep out of reach of children
• Do not use after the expiry date printed on the pack