Diamicron MR Tablet 60mg

About Diamicron MR Tablet 60mg

Diamicron MR Tablet 60mg Uses

• Type 2 diabetes mellitus in adults
• Long term blood sugar control when diet and exercise alone are not enough
• Once daily maintenance therapy for patients already stabilized on Gliclazide
• Combination therapy with Metformin or other antidiabetic medicines

Diamicron MR Tablet 60mg Benefits

• Provides steady 24 hour blood sugar control with a single morning dose
• Reduces the number of tablets needed compared to lower strength options
• Modified release formula lowers the risk of sudden blood sugar swings
• Supports long term HbA1c control alongside diet and exercise

What Experts Say

Gliclazide belongs to the sulfonylurea class of oral antidiabetic drugs. It works by binding to specific receptors on pancreatic beta cells, closing potassium channels and triggering calcium influx that stimulates insulin release. This action helps lower blood glucose in people whose pancreas can still produce insulin but not enough to meet the body's needs.

The modified release matrix in Diamicron MR spreads Gliclazide absorption evenly over 24 hours, so a single 60mg tablet taken with breakfast maintains steady drug levels through the day rather than the sharp peaks seen with immediate release sulfonylureas. This steadier profile is why doctors often move a patient to once daily 60mg or 30mg MR dosing once control is established.

Physicians typically reserve the 60mg strength for patients who need a higher maintenance dose after titration from lower strengths, since the maximum recommended dose is 120mg once daily. Regular HbA1c monitoring and kidney function checks remain part of routine follow up.

Drug Class

• Second Generation Sulfonylurea, Antidiabetic

Diamicron MR Tablet 60mg formula

• Gliclazide

Available forms

• Tablet

How to use Diamicron MR Tablet 60mg?

• Take one tablet by mouth once daily with breakfast
• Swallow the tablet whole with a glass of water, do not crush or chew
• Take it at the same time each day for consistent blood sugar control
• Maximum recommended dose is 120mg, or two 60mg tablets, once daily
• Do not skip breakfast after taking this tablet to avoid low blood sugar

Drug Interactions

• Miconazole, oral or gel form, is contraindicated due to severe hypoglycemia risk
• Other antidiabetic medicines can increase the risk of low blood sugar
• NSAIDs such as ibuprofen can enhance the blood sugar lowering effect
• Alcohol increases the risk of hypoglycemia
• Beta blockers may mask the warning signs of low blood sugar
• Corticosteroids can raise blood sugar and reduce effectiveness
• Warfarin and other anticoagulants may have an enhanced effect when combined
• Danazol raises blood sugar and is generally avoided with Gliclazide

Risks and warnings

• Can cause hypoglycemia, especially if a meal is skipped or delayed
• Not suitable for type 1 diabetes or diabetic ketoacidosis
• Use with caution in elderly patients and those with kidney or liver impairment
• Avoid during pregnancy and breastfeeding unless a doctor advises otherwise
• Use caution when driving or operating machinery due to hypoglycemia risk
• Use with caution in patients with G6PD deficiency
• Tablet must be swallowed whole, never crushed or chewed

Diamicron MR Tablet 60mg Side Effects

• Low blood sugar, symptoms include sweating, shakiness and confusion
• Nausea and mild abdominal pain
• Diarrhea or constipation
• Skin rash or itching
• Mild weight gain
• Dizziness or headache
• Temporary blurred vision when starting treatment
• Rare changes in liver enzyme levels
• Rare reductions in blood cell counts

Storage Conditions

• Store below 30°C in a cool, dry place away from direct sunlight
• Keep the tablet in its original blister strip until it is time to take it
• Keep out of reach of children
• Do not use after the expiry date printed on the pack