Dinaphin Injection 1gm

About Dinaphin Injection 1gm

Dinaphin Injection 1gm Uses

• Severe respiratory infections such as pneumonia and bronchitis caused by susceptible bacteria.
• Urinary tract infections that have not responded to first line oral antibiotics.
• Skin and soft tissue infections, including wound infections after surgery.
• Meningitis and other serious infections of the central nervous system.
• Prevention of infection before certain surgical procedures.

Dinaphin Injection 1gm Benefits

• A broad spectrum of coverage against many common gram positive and gram negative bacteria.
• Once daily dosing in most infections, which improves compliance during hospital stays.
• Effective use in both intramuscular and intravenous forms depending on the setting.
• A well established safety record after decades of use in hospitals across Pakistan.
• Suitability for patients who cannot take oral antibiotics due to vomiting or severe illness.

Hospitals and clinics in Lahore, Karachi, Islamabad, and Rawalpindi rely on ceftriaxone injections for patients admitted with serious infections.

Doctors in Pakistan often choose this antibiotic for typhoid fever, a condition that remains common due to gaps in clean water access.

Dinaphin is administered under medical supervision, usually by a nurse or trained health worker, rather than self injected at home.

Drug Class

• Third generation cephalosporin
• Broad spectrum antibiotic
• Beta lactam antibacterial

Dinaphin Injection 1gm formula

• Ceftriaxone Sodium

Available forms

• Injection

How to use Dinaphin Injection 1gm?

• Dinaphin Injection 1gm is given by a doctor or nurse through a vein or muscle, never self administered.
• The powder is mixed with the correct diluent just before use, following strict sterile technique.
• Dosage and duration depend on the type and severity of infection being treated.
• A full course should be completed even if symptoms improve after a few doses.
• Calcium containing solutions are never mixed or given through the same line as this injection.

Drug Interactions

Several medicines can change how Dinaphin Injection 1gm works, so a doctor should review the full medication list before treatment.

• Calcium Containing Products: Mixing with calcium solutions can form dangerous particles, especially in infants.
• Warfarin: This antibiotic can increase the blood thinning effect of warfarin and raise bleeding risk.
• Aminoglycosides: Combined use is common in severe infections but requires monitoring of kidney function.
• Oral Contraceptives: Antibiotic use may reduce the reliability of hormonal birth control during treatment.

Risks and warnings

• Allergy History: This injection should be avoided in patients with a known allergy to cephalosporins or penicillins.
• Newborn Babies: Ceftriaxone should not be given to newborns who are also receiving calcium containing intravenous fluids.
• Gallbladder Disease: Ceftriaxone can cause biliary sludging, so caution is needed in patients with gallstones.
• Liver Or Kidney Disease: Dose adjustment may be needed in patients with significant liver or kidney impairment.
• Prolonged Diarrhea: Severe or persistent diarrhea during or after treatment should be reported to a doctor promptly.

Side Effects

Dinaphin Injection 1gm is generally well tolerated, though some reactions are common in the days after a dose.

• Pain, redness, or swelling at the injection site
• Diarrhea or an upset stomach
• Nausea or vomiting
• Skin rash
• Vaginal itching or discharge

A smaller number of patients develop more serious reactions that require immediate medical care.

• Severe allergic reaction with swelling of the face, lips, or throat
• Severe watery or bloody diarrhea
• Unusual bruising or bleeding
• Yellowing of the skin or eyes suggesting liver involvement

Storage Conditions

Store the unopened vial below 25 degrees Celsius, away from direct light. Use the prepared solution promptly and discard any unused portion as advised by a pharmacist.