Duragesic Forte Tablet 50mg/650mg

Duragesic Forte Uses

Duragesic Forte is used for the treatment of pain or muscle spasms due to multiple sclerosis or spinal cord injury or disease. It is used to treat rheumatological conditions, orthopedic and traumatic disorders. Moreover, it helps gain muscle tone and reduces soreness and stiffness.

Duragesic Forte Tablet 50mg/650mg formula

• Paracetamol
• Orphenadrine Citrate

Available forms

• Tablets

Risks and warnings

You should know the risks and warnings of Duragesic Forte to prevent its misuse.

There are some specific circumstances under which the use of certain medications is contraindicated or considered dangerous. So if you are taking any medicine its always a good practice to familiarize yourself with its risks and warnings.

The risks and warnings associated with Duragesic Forte are:

1. Allergic to Paracetamol or Orphenadrine Citrate

If you are allergic to paracetamol or orphenadrine citrate, do not take Duragesic Forte or any other medicine with the same generic name, as it can result in a life-threatening condition called anaphylactic shock.

2. Skin reaction

If you ever have had a skin reaction known as Steven Johnson syndrome upon Paracetamol intake, do not take Duragesic Forte. Tell your healthcare provider your complete medical history. 

3. Alcohol intake

If you drink more than three glasses of alcohol in a day, take paracetamol with caution as it increases the chances of liver damage.

If you drink alcohol, discuss it with a healthcare provider before taking Orphenadrine Citrate, as it can make you feel dizzy.

4. Glucose 6 phosphate dehydrogenase deficiency

Patients who have a condition called glucose 6 phosphate dehydrogenase deficiency, must take Duragesic Forte with extreme caution as it can cause hemolysis.

5. Malnutrition

People suffering from long-term malnutrition must take paracetamol with caution.

6. Asthma

If you are asthmatic, take Duragesic Forte with caution.

7. Low blood pressure

If you have a history of low blood pressure or if you are taking medicines to control high blood pressure, you must take orphenadrine citrate with caution.

8. Kidney disease

If you have kidney disease, take orphenadrine citrate with caution as it can worsen the preexisting condition. Do not forget to tell your healthcare provider about it.

9. Liver diseases

Patients with liver disease should take Duragesic Forte with caution. It is because your liver helps in the metabolism and excretion of drugs. When it does not work properly due to any disease, it can cause accumulation of the drug in your body, leading to severe adverse effects.

10. Sedatives

If you are already taking sedatives or sleeping aids, take Duragesic Forte with caution as orphenadrine can make you feel dizzy.

11. Pregnancy and breastfeeding

If you are pregnant, do not take Duragesic Forte unless your doctor advises it. It can affect the health of your baby. Breastfeeding mothers should also consult with a healthcare provider before taking it.

12. Operating machinery

Do not drive a car or operate any machinery while you take Duragesic Forte, as it can cause sedation, which can eventually lead to accidents.

How to use Duragesic Forte Tablet 50mg/650mg?

• Take Duragesic Forte tablet with a glass of water and swallow it whole. Follow the instructions given by your doctor.
• Do not use Duragesic Forte after the mentioned expiry date.
• It is better to take it with food. But you can also take it on an empty stomach.
• Duragesic Forte should be taken as prescribed by your healthcare provider. Mostly it is prescribed twice or thrice a day.

Duragesic Forte Side Effects

Patients taking Duragesic Forte may experience any of the following side effects:

• Shortness of breath
• Rashes
• Swelling
• Dizziness
• Hives
• Decreased white blood cells
• Decreased red blood cells
• Decreased platelets
• Cough
• Disorientation
• Arrhythmia
• Dizziness
• Dry mouth
• Fatigue
• Hypotension
• Sleepiness
• Drowsiness
• Nausea
• Vomiting
• Dry eyes
• Nasal congestion

Drug Interactions

Duragesic Forte may interact with the following drugs. A drug interaction does not mean that you stop taking the medicine on your own. But, you must tell your healthcare provider about it.

• Lomitapide
• Tetracaine
• Warfarin
• Flibanserin
• Imatinib
• Isoniazid
• Axitinib
• Mipomersen
• Busulfan
• Dapsone topical
• Eltrombopag
• Exenatide injectable solution and suspension
• Ivacaftor
• Daclizumab
• Lixisenatide
• Propoxyphene

To avoid drug interactions, you must give a complete history to the healthcare provider about other health conditions you have and what medicines you have been taking. At times, a dose adjustment can help prevent drug interaction.

Storage Conditions

• Keep the product out of the reach and sight of children.
• Store it at room temperature.
• Do not use it after the mentioned expiry date.