Flagyl Plus Tablet 250mg / 200mg

About Flagyl Plus Tablet 250mg / 200mg

Flagyl Plus Tablet 250mg / 200mg Uses

• Treatment of intestinal amoebiasis caused by Entamoeba histolytica
• Clearing both the active infection and the cyst carrier stage of amoebiasis
• Treatment of giardiasis, a common parasitic diarrhea
• Treatment of amoebic dysentery with blood or mucus in stool
• Prevention of relapse after an amoebic liver abscess has been treated

Flagyl Plus Tablet 250mg / 200mg Benefits

• Combines an amoebicidal drug with a cyst clearing drug in a single tablet
• Reduces the chance of silent cyst carriage after symptoms resolve
• Useful in regions where contaminated water and food make reinfection common
• Available as an affordable, widely stocked tablet across Pakistan

What Experts Say

Doctors combine metronidazole with diloxanide furoate because the two drugs target different stages of amoebic infection. Metronidazole clears the invasive trophozoite form circulating in tissue, while diloxanide furoate acts inside the bowel to eliminate the cyst form that metronidazole alone often leaves behind.

This dual action matters in Pakistan, where reinfection from contaminated water and food is common and cyst carriage without treatment can silently continue for months. Using only an amoebicidal drug like metronidazole can end symptoms while leaving a person still capable of passing cysts to others.

Physicians usually confirm improvement through resolution of loose stools, abdominal cramping, and blood or mucus in stool before considering the course complete. A stool examination after treatment is sometimes advised to confirm the cysts have genuinely cleared, especially when symptoms were severe or prolonged before treatment began.

Drug Class

• Nitroimidazole Antiprotozoal
• Amoebicide
• Antidiarrheal Combination

Flagyl Plus Tablet 250mg / 200mg formula

• Metronidazole + Diloxanide Furoate

Available forms

• Tablet

How to use Flagyl Plus Tablet 250mg / 200mg?

• Take exactly as prescribed by the treating doctor
• Swallow the tablet whole with a full glass of water
• Take with food to reduce stomach upset
• Complete the full course even after symptoms improve
• Avoid alcohol during treatment and for at least two days after the last dose
• Do not double the dose if a dose is missed, simply continue the regular schedule

Drug Interactions

• Alcohol: Causes a disulfiram like reaction with flushing, nausea, and rapid heartbeat
• Warfarin: Metronidazole can increase the blood thinning effect and bleeding risk
• Lithium: Levels can rise and increase the risk of lithium toxicity
• Phenytoin and Phenobarbital: These can lower Metronidazole levels and reduce its effect
• Cimetidine: Can raise Metronidazole blood levels by slowing its breakdown

Risks and warnings

• Allergy: Avoid if there is a known allergy to Metronidazole or Diloxanide Furoate
• Alcohol: Do not consume alcohol during treatment, it can cause severe nausea and flushing
• Liver Disease: Use with caution and under close supervision in patients with liver impairment
• Nervous System Disorders: Use carefully in patients with a history of seizures or nerve disease
• Blood Disorders: Use with caution in patients with a history of low blood cell counts
• Pregnancy: Use only if clearly needed and advised by the treating doctor
• Breastfeeding: Discuss with a doctor, since Metronidazole passes into breast milk

Flagyl Plus Tablet 250mg / 200mg Side Effects

• Nausea or vomiting
• Metallic taste in the mouth
• Loss of appetite
• Stomach cramps or bloating
• Headache
• Dizziness
• Dark colored urine
• Dry mouth
• Severe allergic reaction with rash, swelling, or breathing difficulty
• Numbness or tingling in the hands or feet with prolonged use
• Seizures, rare and mostly with high doses

Storage Conditions

• Store below 30 degrees Celsius in a cool, dry place
• Keep the strip inside its original foil packaging until use
• Protect from direct sunlight and moisture
• Keep out of reach of children
• Do not use tablets past the printed expiry date