About Flucate Injection 25mg
Flucate Injection contains Fluphenazine Decanoate, a phenothiazine antipsychotic used for chronic schizophrenia.
Flucate Injection 25mg Uses
- Maintenance treatment of chronic schizophrenia
- Long term management of other chronic psychotic disorders
- Control of hallucinations, delusions and disorganized thinking in psychosis
- Suitable for patients who need a long acting depot antipsychotic instead of daily oral tablets
Flucate Injection 25mg Benefits
- Provides steady drug levels over two to four weeks with a single injection
- Reduces the risk of relapse linked to missed daily doses
- Improves long term treatment adherence in patients with chronic psychosis
- Lowers the daily pill burden for patients and caregivers
What Experts Say
Fluphenazine decanoate is a long acting depot antipsychotic that belongs to the phenothiazine class. It works by blocking dopamine D2 receptors in the brain, which helps reduce hallucinations, delusions and disorganized thinking linked to chronic psychosis.
Psychiatrists in Pakistan often prefer a depot injection like Flucate for patients who struggle to take daily oral antipsychotics as prescribed. Since schizophrenia usually needs long term treatment, missing even a few doses of an oral tablet can trigger a relapse, while one injection maintains steady drug levels for two to four weeks and reduces the burden of daily pill taking on patients and caregivers.
Doctors typically start treatment with a small test dose to rule out an allergic reaction before moving to the full maintenance dose. Regular follow up visits let the treating psychiatrist track movement related side effects, mood changes and overall response, and adjust the dosing interval or dose strength when needed for safe long term care.
Drug Class
- Phenothiazine antipsychotic (typical antipsychotic, depot injection)
Flucate Injection 25mg Uses in Urdu
- دائمی شیزوفرینیا کے علاج میں استعمال ہوتا ہے
- ذہنی امراض میں وہم اور فریب نظر کم کرنے کے لیے دیا جاتا ہے
- سوچ میں الجھن اور غیر منظم خیالات کو قابو کرنے میں مدد دیتا ہے
- ان مریضوں کے لیے مفید ہے جو روزانہ گولی باقاعدگی سے نہیں کھا پاتے
- دماغی امراض کے طویل المدتی علاج کا حصہ ہے
Flucate Injection 25mg formula
How to use Flucate Injection 25mg?
- Given only by a trained healthcare professional as a deep intramuscular injection
- Never inject this medicine into a vein
- Usual dosing interval is every two to four weeks, set by the treating psychiatrist
- A small test dose may be given first to check for sensitivity before starting regular treatment
- Do not stop or change the injection schedule without medical advice
- Report new muscle stiffness, high fever or confusion to the doctor right away
Drug Interactions
- Alcohol And Sedatives: Combining Flucate with alcohol, sleeping pills or opioid painkillers can cause extreme drowsiness and slowed breathing.
- Other Antipsychotics Or Antidepressants: Using them together can raise the risk of heart rhythm changes and increased side effects.
- Antihypertensive Medicines: Fluphenazine can add to the blood pressure lowering effect of these drugs.
- Lithium: Combined use has been linked to confusion and nervous system side effects in some patients.
- Anticholinergic Drugs: Medicines used for allergies, motion sickness or stomach cramps can worsen dry mouth, blurred vision and constipation.
- Epinephrine: Fluphenazine can reverse the normal blood pressure raising effect of epinephrine, leading to unexpected low blood pressure.
Risks and warnings
- Neuroleptic Malignant Syndrome: A rare but life threatening reaction with high fever, muscle rigidity and confusion that needs emergency care.
- Tardive Dyskinesia: Long term use can cause repetitive, involuntary movements of the face and body that may not fully reverse.
- Elderly Patients With Dementia: This medicine is not approved for dementia related psychosis in older adults due to a higher risk of serious complications.
- Heart Rhythm Changes: Fluphenazine can affect heart rhythm, so caution is needed in patients with existing heart disease.
- Low Blood Pressure: The injection can cause a sudden drop in blood pressure, especially when standing up quickly.
- Pregnancy And Breastfeeding: Use only if clearly needed, since the baby may develop withdrawal or movement symptoms after birth.
- Liver Or Kidney Disease: Dose adjustment and closer monitoring may be required in patients with reduced liver or kidney function.
Flucate Injection 25mg Side Effects
- Drowsiness or sedation
- Dry mouth
- Blurred vision
- Constipation
- Dizziness on standing up (orthostatic hypotension)
- Muscle stiffness, tremor or restlessness (extrapyramidal symptoms)
- Weight gain
- Menstrual changes or unusual breast milk production due to raised prolactin
- Pain, redness or swelling at the injection site
- Skin sensitivity to sunlight
- Tardive dyskinesia with long term use
- Neuroleptic malignant syndrome in rare cases
Storage Conditions
- Store the ampoule at room temperature, below 30°C, away from direct heat
- Protect the ampoule from light by keeping it in its original carton until use
- Do not freeze the injection
- Keep out of reach and sight of children
- Use the ampoule only once and discard any unused portion after opening
- Check the solution for discoloration or particles before injecting
