Fluclox Injection 500mg

About Fluclox Injection 500mg

Fluclox Injection 500mg Uses

• Treatment of skin and soft tissue infections such as cellulitis, boils, and abscesses
• Treatment of bone and joint infections including osteomyelitis
• Treatment of respiratory tract infections caused by susceptible bacteria
• Treatment of wound infections after surgery or injury
• Treatment of ear, nose, and throat infections caused by staphylococci

Fluclox Injection 500mg Benefits

• Effective against penicillin resistant staphylococcus bacteria
• Fast acting when given intravenously or intramuscularly in hospital settings
• Narrow spectrum action causes less disruption to normal gut bacteria compared to broader antibiotics
• Well established safety profile from decades of clinical use
• Suitable for patients unable to take oral antibiotics

What Experts Say

Flucloxacillin belongs to a group of antibiotics called penicillinase resistant penicillins. It works by blocking the enzymes bacteria need to build their cell walls, which causes the bacteria to weaken and die. This specific structure makes it effective against staphylococcus strains that would otherwise destroy standard penicillin.

Doctors often choose this injection when an infection is confirmed or strongly suspected to be caused by staphylococcus bacteria, particularly in skin, soft tissue, bone, or wound infections. The injectable form is preferred when rapid, high blood levels of the antibiotic are needed or when a patient cannot take oral medicine.

Patients are advised to complete the full course exactly as prescribed, since stopping early can allow bacteria to survive and become resistant. Doctors also watch for rare but important liver related side effects, and anyone with a known penicillin allergy should never receive this medicine.

Drug Class

• Penicillinase Resistant Penicillin (Narrow Spectrum Antibiotic)

Fluclox Injection 500mg formula

• Flucloxacillin

Available forms

• Injection

How to use Fluclox Injection 500mg?

• Administered only by a doctor or trained healthcare professional via intramuscular or intravenous injection
• Dose and frequency depend on the severity and type of infection being treated
• Complete the full prescribed course even if symptoms improve early
• Inform your doctor about any allergies before the first dose is given
• Report any signs of rash, breathing difficulty, or swelling immediately

Drug Interactions

• Warfarin: Flucloxacillin may alter the blood thinning effect, requiring closer monitoring of clotting tests.
• Methotrexate: Concurrent use can increase methotrexate levels and toxicity risk.
• Probenecid: Increases flucloxacillin blood levels by reducing its elimination from the body.
• Oral Contraceptives: Antibiotic use may reduce the effectiveness of hormonal birth control in rare cases.

Risks and warnings

• Penicillin Allergy: Should not be used in patients with a known allergy to penicillin or related antibiotics.
• Liver Disease: Use with caution since flucloxacillin can rarely cause liver injury, more common in patients over 55 years or with prolonged courses.
• Kidney Impairment: Dose adjustment may be required in patients with reduced kidney function.
• Pregnancy And Breastfeeding: Should only be used if clearly needed and advised by a doctor.
• Prolonged Use: Extended courses increase the risk of liver problems and should be monitored closely.

Fluclox Injection 500mg Side Effects

• Nausea and vomiting
• Diarrhea and stomach upset
• Skin rash or itching
• Pain or swelling at the injection site
• Allergic reactions ranging from mild rash to severe anaphylaxis
• Liver related side effects such as jaundice, especially with prolonged use
• Clostridioides difficile associated diarrhea in rare cases

Storage Conditions

• Store the vial at room temperature between 15 and 30 degrees Celsius
• Protect from light and moisture
• Do not use if the powder has changed color or the vial is damaged
• Keep out of reach of children
• Discard reconstituted solution after the time period advised by the pharmacist