Gen-M suspension 15mg / 90mg

About Gen-M suspension 15mg / 90mg

Gen-M Suspension 15mg / 90mg Uses

• Treats uncomplicated malaria caused by Plasmodium falciparum in children
• Used for mixed malaria infections involving more than one parasite type
• Clears malaria parasites from the blood in children who can take oral medicine
• Prevents progression of uncomplicated malaria to severe disease

Gen-M Suspension 15mg / 90mg Benefits

• Easy to swallow liquid form suited for young children who cannot take tablets
• Combines two antimalarials for a stronger, more reliable cure rate
• Short 3 day course improves the chance that children complete full treatment
• Lower relapse risk compared to single drug antimalarial therapy

What Experts Say

Artemether combined with lumefantrine is one of the most widely used artemisinin combination therapies for uncomplicated falciparum malaria in children. Artemether clears the bulk of parasites quickly, while lumefantrine has a longer action that mops up any parasites left behind, which lowers the chance of the infection coming back.

Doctors calculate the suspension dose by body weight rather than age, since children of the same age can weigh very differently, especially where malnutrition is common. Giving the dose with milk or a fatty snack improves how well lumefantrine is absorbed, so caregivers are usually advised to give it right after a meal rather than on an empty stomach.

Physicians recommend completing all six doses over three days even if the child's fever settles after the first day or two, because stopping early is one of the most common causes of treatment failure and drug resistance. A repeat blood test a few days after finishing treatment confirms the parasites have fully cleared.

Drug Class

• Antimalarial (Artemisinin combination therapy)

Gen-M suspension 15mg / 90mg formula

• Artemether + Lumefantrine

Available forms

• Suspension

How to use Gen-M suspension 15mg / 90mg?

• Dose is calculated by the child's body weight, not age
• Standard course is 6 doses given over 3 days, at 0, 8, 24, 36, 48, and 60 hours
• Give each dose with milk or a fatty meal to help the body absorb it properly
• Shake the bottle well before measuring each dose
• Use the measuring cup or spoon provided, not a household spoon
• Complete the full 3 day course even if symptoms improve early

Drug Interactions

• Antifungal azoles: Ketoconazole and similar drugs can raise lumefantrine levels and increase side effects
• Grapefruit juice: Can affect drug metabolism and should be avoided during treatment
• Other QT prolonging drugs: Combining with certain antibiotics or antiarrhythmics raises heart rhythm risk
• Mefloquine: Not recommended together due to overlapping antimalarial action and interaction risk

Risks and warnings

• Heart rhythm: Can affect heart electrical activity (QT interval), so caution is needed in children with existing heart conditions
• Empty stomach use: Taking it without food reduces how well it works, so it should always be given with milk or a meal
• Severe malaria: Not suitable for severe or complicated malaria, which needs injectable treatment instead
• Liver conditions: Use with caution in children with existing liver disease
• Repeat dosing: A missed or vomited dose within one hour should be repeated to keep the full course effective

Gen-M Suspension 15mg / 90mg Side Effects

• Loss of appetite
• Nausea and vomiting
• Abdominal pain
• Headache and dizziness
• Sleep disturbances
• Mild rash or itching
• Cough
• Palpitations (rare)

Storage Conditions

• Store below 30°C in a cool, dry place
• Keep the bottle tightly closed when not in use
• Do not refrigerate or freeze
• Discard any unused suspension after the course is finished
• Keep out of reach of children