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Price of Grasil Injection 500mg
The price of Grasil Injection 500mg in Pakistan is Rs. 355
Grasil Injection Uses
Grasil injection is an antibiotic medication used to treat bacterial infections like urinary tract infections, sinusitis, otitis media, upper and lower respiratory tract infections, typhoid fever, etc.
Grasil injection is composed of Amikacin, which is an aminoglycoside antibiotic that works by inhibiting the protein synthesis of the bacteria. It binds to 30S ribosome of the bacteria and interferes with its growth. Aminoglycosides are broad-spectrum antibiotics that work against both gram-positive and gram-negative bacteria. It is an antibiotic, therefore, used against bacterial infections only. They are not given in viral or fungal infections.
How to use Grasil Injection 500mg?
- The injection should be administered by or under the supervision of a health care professional.
- The frequency and dosage depends on your symptoms and response to the treatment
- The dose of Grasil injection for adults is 15mg/kg/day, administered as a single dose or divided into two doses by 12 hours interval given IM or IV
- Grasil injection is injected intravenously or intramuscularly. For intramuscular administration, the healthcare provider will inject it deep into your muscles of the upper quadrant of the buttock due to its thick viscosity. They will make sure it is not injected near the artery or a nerve.
- For intravenous injection, they will infuse it over 30 minutes
- Do not use it after the expiration date
Grasil Injection Side Effects
The common side effects of Grasil injection are:
- Abdominal pain
- Vomit containing coffee grounds
- Blood in stool
- Constipation
- Black stools
- Acid reflux
- Anemia
- Elevation of liver enzymes
- Diarrhea
- Serum sickness
- Risk of infections
- Crystalluria
- Eye discomfort
- Gastric discomfort
- Lethargy and body pain
- Headache
- Hearing impairment
- Nausea
- Pancreatitis
- Sleep disorders
- Vision disorders
- Altered taste
- Kidney function impairment
- Neuromuscular blockade
- Ototoxicity
Drug Interactions
Grasil injection can interact with the following drugs so co-administration should be done with caution:
- Blood thinners like warfarin
- Allopurinol
- Oral birth control pills containing estrogen and progesterone
- Other antibiotics like chloramphenicol, tetracyclines, sulfonamides, and macrolides
- Cholesterol-lowering drugs like atorvastatin, rosuvastatin, and other statins
- Ergot alkaloids
- Colchicine
- Oral hypoglycemicagents like repaglinide, rosiglitazone, nateglinide, and pioglitazone
- Quetiapine
- Antiarrhythmic drugs like amiodarone and procainamide
- Benzodiazipine like diazepam, midazolam and triazolam
- Calcium containing supplements
- Iron supplements
- Zinc and bismuth-containing drugs
- To avoid drug interactions, you must give a complete history to the healthcare provider about other health conditions you have and what medicines you have been taking. At times, a dose adjustment can help prevent drug interactions.
Storage Conditions
- Store the medicine at room temperature
- Keep out of reach and sight of children
- Protect it from sunlight and moisture
Disclaimer
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