Home Medicine
Gravibinan Injection 2ml
Gravibinan Injection 2ml

Gravibinan Injection 2ml

Generic Name: Hydroxyprogesterone Caproate + Estradiol Valerate

Injection Prescription Required
Manufacturer Bayer
Formula Hydroxyprogesterone Caproate + Estradiol Valerate

Price

PKR 727

per pack

Consult a Doctor

About Gravibinan Injection 2ml

Gravibinan is a hormonal injection combining progesterone and estrogen to prevent preterm birth and support pregnancy.

Gravibinan Injection Uses

  • Preventing preterm birth in women with a history of early delivery
  • Managing threatened miscarriage and pregnancy loss risk
  • Providing hormonal support during pregnancy complications
  • Maintaining healthy hormone levels in at-risk pregnancies
  • Supporting endocrine balance to reduce miscarriage risk

Gravibinan Injection Benefits

  • Reduces the risk of early delivery in high-risk pregnancies
  • Supports progesterone levels crucial for pregnancy maintenance
  • Helps protect developing fetus during critical early months
  • Prescribed by obstetricians for proven effectiveness
  • Combines progesterone and estrogen for complete hormonal support

What Experts Say

Hydroxyprogesterone caproate is a synthetic progesterone that maintains the uterine lining essential for pregnancy. Estradiol valerate provides estrogen support. Together, these hormones stabilize the hormonal environment needed for healthy pregnancy continuation and reduce the likelihood of premature labor.

Obstetricians recommend Gravibinan for women with recurrent miscarriages or histories of preterm delivery. Research shows regular injections significantly reduce preterm birth rates in susceptible patients. The medication is administered intramuscularly and works systemically to support pregnancy.

Gravibinan is generally well-tolerated in pregnancy when prescribed appropriately. Medical monitoring ensures maternal and fetal safety throughout treatment. The benefits for at-risk pregnancies typically far outweigh potential risks.

Drug Class

  • Hormonal Combination (Progestin + Estrogen)

Packaging and Quantity

  • 2 ml ampoule injection (250 mg Hydroxyprogesterone Caproate + 5 mg Estradiol Valerate)

When Not to Use Gravibinan

  • Allergy to hydroxyprogesterone caproate or estradiol valerate
  • History of blood clots or thromboembolic disorders
  • Breast cancer or estrogen-dependent tumors
  • Undiagnosed vaginal bleeding
  • Severe liver disease or active liver malignancy

Gravibinan Injection Uses in Urdu

Gravibinan 2ml Injection ایک مرکب دوا ہے جو ان خواتین میں قبل از وقت پیدائش کو روکنے کے لیے استعمال کی جاتی ہے جن کی قبل از وقت پیدائش ہوئی ہے۔ اس میں Hydroxyprogesterone Caproate اور Estradiol Valerate ہوتے ہیں۔ Hydroxyprogesterone Caproate پروجیسٹرون کی ایک مصنوعی شکل ہے، یہ ہارمون صحت مند حمل کو برقرار رکھنے کے لیے اہم ہے، جبکہ Estradiol Valerate ایسٹروجن کی ایک شکل ہے۔ دوا قبل از وقت ڈیلیوری کی تاریخ والی خواتین میں قبل از وقت ڈیلیوری کے خطرے کو کم کرکے کام کرتی ہے۔

Gravibinan Injection 2ml formula

  • Hydroxyprogesterone Caproate + Estradiol Valerate

Available forms

  • Injection

How to use Gravibinan Injection 2ml?

  • Administered by intramuscular injection as prescribed by your obstetrician
  • Typically given weekly or as directed by your doctor
  • Must only be injected by a qualified healthcare professional
  • Should not be injected intravenously
  • Continue injections for entire duration recommended by your doctor
  • Do not stop treatment without medical consultation

Contraindications

The medication should not be used in patients with a history of:

  • Blood clots
  • Liver disease
  • Breast cancer

Drug Interactions

  • Blood thinners: May increase clotting risk. Tell your doctor about all medications.
  • Other hormonal medications: Avoid concurrent use unless specifically approved by your obstetrician.
  • Medications affecting liver function: May alter hormone metabolism. Discuss with your doctor.

Risks and warnings

  • Blood clot risk: Estrogen-containing products slightly increase clotting risk. Report leg pain or swelling immediately.
  • Migraine history: Tell your doctor if you have a history of migraines, particularly with aura.
  • Heart or stroke history: Discuss any history of heart disease or stroke with your obstetrician.
  • High blood pressure: Monitor blood pressure regularly during treatment.
  • Liver disease: Inform your doctor of any liver problems before use.

Gravibinan Injection Side Effects

Most women tolerate Gravibinan well. Common mild side effects may include:

  • Injection site pain or redness
  • Mild nausea or stomach upset
  • Breast tenderness
  • Mild headache
  • Mood changes

Serious side effects are rare. Seek immediate medical help if you experience:

  • Signs of blood clots: leg pain, swelling, or shortness of breath
  • Severe allergic reaction with rash or difficulty breathing
  • Abdominal pain or severe headache
  • Vision changes or chest pain

Storage Conditions

  • Store at room temperature between 15-25 degrees Celsius
  • Keep away from direct sunlight and moisture
  • Do not freeze
  • Keep in original packaging
  • Keep out of reach of children
  • Do not use after expiration date

⚠️ Medical Disclaimer

oladoc aspires to publish the most authentic and error-free content regarding medicines and other healthcare products. Our team of experts thoroughly reviews the content from time to time to ensure it is medically accurate and up to date. However, any information provided on the oladoc website is not intended to be used as a substitute for advice from a healthcare professional. The content mentioned here only serves to provide basic information and may not encompass all possible side effects, precautions, risks, warnings, or drug interactions. We encourage you to always consult your doctor for medical advice.

Frequently Asked Questions

What is the price of Gravibinan Injection 2ml in Pakistan?

The Gravibinan Injection 2ml price in Pakistan is Rs. 727

What is Gravibinan Injection 2ml used for?

Gravibinan Injection 2ml is used in the following conditions:
  • Prevention of preterm birth in high-risk pregnancies
  • Management of threatened miscarriage
  • Hormonal support during pregnancy complications
  • Recurrent miscarriage prevention
  • Gynecological support during pregnancy

What is Gravibinan Injection 2ml composed of?

Gravibinan Injection 2ml is composed of:
  • Hydroxyprogesterone Caproate + Estradiol Valerate

Do you need a prescription to buy Gravibinan Injection 2ml?

To buy Gravibinan Injection 2ml you must have a prescription signed by your doctor.