Haemaccel Infusion 500ml

About Haemaccel Infusion 500ml

Haemaccel Infusion 500ml Uses

• Treatment of hypovolemic shock caused by severe blood loss
• Fluid replacement in shock from burns, peritonitis, or pancreatitis
• Volume support after crush injuries with significant fluid loss
• Replacement of circulating volume during major surgery with blood loss
• Fluid resuscitation in shock caused by severe diarrhea or dehydration
• Priming solution for extracorporeal circulation and isolated organ perfusion

Haemaccel Infusion 500ml Benefits

• Restores circulating blood volume quickly during an emergency
• Does not require blood group cross matching before use
• Carries no risk of viral transmission unlike donor blood products
• Can be started immediately while donor blood is being arranged
• Helps stabilize blood pressure until definitive treatment is given

What Experts Say

Polygeline is a modified fluid gelatin colloid with an average molecular weight of roughly 30,000 to 35,000 Daltons. Once infused, it stays largely within the blood vessels and exerts oncotic pressure that pulls fluid into the vascular space, which restores circulating blood volume quickly during hypovolemic shock.

Gelatin colloids have a shorter intravascular retention time than albumin or synthetic starches, so their volume effect is not as prolonged. This tradeoff is accepted in emergency settings because the solution requires no cross matching, carries no risk of blood borne infection transmission, and can be started immediately while donor blood is arranged.

Gelatin based plasma expanders are known to trigger histamine release and anaphylactoid reactions in a small percentage of patients, which is why clinicians infuse the first 10 to 20 milliliters slowly and monitor closely. Large volume infusion also dilutes clotting factors, so the benefit of rapid volume restoration is always weighed against bleeding risk and cardiac or renal fluid tolerance.

Drug Class

• Plasma Volume Expander
• Colloid Solution

Haemaccel Infusion 500ml formula

• Polygeline

Available forms

• Infusion

How to use Haemaccel Infusion 500ml?

• Administered only by a doctor or trained healthcare provider through intravenous infusion
• Given in a hospital or emergency care setting under continuous monitoring
• Infusion rate and total volume are decided by the treating doctor based on blood loss and vital signs
• First 10 to 20 milliliters given slowly to watch for an allergic reaction
• Vital signs, urine output, and fluid balance are monitored throughout the infusion
• Bottle is checked for particulate matter or discoloration before use

Drug Interactions

• Cardiac Glycosides: Calcium content may increase the effect of digoxin or digitoxin, raising the risk of an irregular heartbeat.
• Citrated Blood Products: Calcium in this solution can counteract the anticoagulant effect of citrate and cause clotting if mixed in the same line.
• Other IV Fluids: Generally compatible with saline, dextrose, and heparinized blood, but should not be mixed directly with other drugs in the same infusion bottle.

Risks and warnings

• Anaphylactoid Reactions: Gelatin based solutions can trigger histamine release causing skin flushing, itching, low blood pressure, or rarely severe anaphylactic shock.
• Fluid Overload: Large volume infusion can worsen heart failure, high blood pressure, or kidney impairment by overloading the circulation.
• Coagulation Dilution: Infusing large volumes can dilute clotting factors and platelets, increasing bleeding risk during surgery or trauma.
• Calcium Content: Contains calcium chloride, so it should not be given through the same line as citrated blood products because clotting can occur.
• Renal Impairment: Used cautiously in patients with reduced kidney function due to risk of fluid and electrolyte buildup.
• Pulmonary Edema: Avoided in patients with existing fluid in the lungs or severe breathing difficulty.

Haemaccel Infusion 500ml Side Effects

• Skin rash, redness, or itching at or away from the infusion site
• Low blood pressure or a fast heartbeat during infusion
• Nausea or vomiting
• Shivering or a mild rise in body temperature
• Shortness of breath
• Swelling at the injection site
• Rare but serious anaphylactic reaction with facial swelling, wheezing, or shock

Storage Conditions

• Store below 25 degrees Celsius at room temperature
• Protect from direct light and from freezing
• Inspect the bottle for particulate matter or discoloration before use
• Discard the bottle if the seal is broken or the solution appears cloudy
• Use immediately once opened and discard any unused portion
• Keep out of reach of children