Juvia-M Plus Tablet 50mg / 1000mg

About Juvia-M Plus Tablet 50mg / 1000mg

Juvia-M Plus Tablet 50mg / 1000mg Uses

• Type 2 diabetes mellitus, alongside diet and exercise
• Blood sugar control when metformin alone is not enough
• Combination therapy to reduce HbA1c levels

Juvia-M Plus Tablet 50mg / 1000mg Benefits

• Combines two complementary mechanisms in one tablet
• Improves treatment adherence with a simpler dosing routine
• Sitagliptin component carries a low risk of hypoglycemia on its own

What Experts Say

Sitagliptin belongs to the DPP-4 inhibitor class of antidiabetic drugs. It works by blocking the enzyme that breaks down incretin hormones in the gut, which allows the body to release more insulin after meals while reducing excess glucose output from the liver. This effect is glucose dependent, meaning it works mainly when blood sugar is already high.

Metformin, the second active ingredient, lowers blood sugar mainly by reducing glucose production in the liver and improving how muscle cells respond to insulin. Combining the two mechanisms in one tablet allows many patients to reach their blood sugar targets with a single combined dose instead of two separate medicines.

Clinical evidence shows this combination is generally well tolerated, with mild stomach upset being the most common complaint during the first few weeks of treatment. Because metformin carries a small but recognized risk of lactic acidosis, doctors usually check kidney function before starting therapy and review it periodically during long term use, especially in older patients.

Drug Class

• DPP-4 inhibitor (Sitagliptin)
• Biguanide antidiabetic (Metformin)

Juvia-M Plus Tablet 50mg / 1000mg formula

• Sitagliptin + Metformin

Available forms

• Tablet

How to use Juvia-M Plus Tablet 50mg / 1000mg?

• Take with a meal to reduce stomach upset
• Swallow the tablet whole, do not crush or chew it
• Take at the same time each day as advised by the doctor
• Continue diet and exercise recommendations alongside this medicine
• Do not double the dose if a dose is missed

Drug Interactions

• Sulfonylureas and insulin: Increase the risk of low blood sugar when used together.
• Alcohol: Raises the risk of lactic acidosis and low blood sugar.
• Iodinated contrast dye: May increase kidney related risk when combined with metformin.
• Diuretics: Certain water pills can affect kidney function and change how the medicine is cleared.
• Corticosteroids: Can raise blood sugar and reduce the medicine's effectiveness.

Risks and warnings

• Lactic acidosis: A rare but serious risk linked to the metformin component, more likely with kidney or liver impairment.
• Kidney function: Doctors check kidney function before starting and periodically during treatment.
• Pancreatitis: Sitagliptin has been linked to rare cases of pancreas inflammation, so persistent stomach pain needs medical review.
• Vitamin B12: Long term metformin use can lower vitamin B12 levels over time.
• Contrast dye procedures: The medicine may need to be paused around imaging tests that use iodinated contrast.

Juvia-M Plus Tablet 50mg / 1000mg Side Effects

• Nausea or stomach upset
• Diarrhea
• Loss of appetite
• Headache
• Upper respiratory symptoms
• Low blood sugar when combined with other diabetes medicines
• Metallic taste in the mouth

Storage Conditions

• Store below 30 degrees Celsius in a dry place
• Keep the strip away from direct sunlight and moisture
• Keep out of reach of children
• Do not use after the expiry date printed on the pack