About Kast Tablet 10 mg
Kast Tablet is a leukotriene receptor antagonist containing Montelukast Sodium, used for asthma and allergy control.
Kast Tablet 10 mg Uses
- Long term control and prevention of asthma symptoms in adults and adolescents
- Prevention of exercise induced bronchoconstriction
- Relief of seasonal and perennial allergic rhinitis symptoms such as sneezing and nasal congestion
- Add on therapy alongside inhaled corticosteroids for persistent asthma that is not fully controlled
Kast Tablet 10 mg Benefits
- Reduces the frequency and severity of asthma flare ups with once daily dosing
- Improves airflow by easing airway swelling and mucus buildup
- Offers a steroid free option for patients sensitive to inhaled corticosteroids
- Eases nasal itching, sneezing and congestion linked to allergic rhinitis
- Convenient oral tablet that does not require inhaler technique
What Experts Say
Montelukast sodium works by blocking the cysteinyl leukotriene type 1 receptor found in airway smooth muscle and immune cells. Leukotrienes are inflammatory chemicals released during allergic and asthmatic reactions that trigger bronchoconstriction, mucus production and airway swelling.
This mechanism makes it a maintenance therapy rather than a rescue treatment for acute attacks. Clinical evidence supports once daily evening dosing, with steady state effects building over the first few days of regular use. It is often paired with inhaled corticosteroids for persistent asthma or used alone for allergic rhinitis.
Regulatory bodies have flagged neuropsychiatric events including mood changes, sleep disturbances and rare suicidal thinking as a class effect of leukotriene receptor antagonists. Clinicians weigh this risk against the drug's favorable tolerability profile for patients who cannot use inhaled steroids or need extra allergy control.
Drug Class
- Leukotriene Receptor Antagonist (LTRA)
Kast Tablet 10 mg Uses in Urdu
- دمہ کی علامات کو طویل عرصے تک قابو میں رکھنے کے لیے
- ورزش کی وجہ سے سانس کی نالی سکڑنے سے بچاؤ کے لیے
- موسمی اور غیر موسمی الرجی ناک کی سوزش کی علامات جیسے چھینکیں اور ناک بند ہونے میں آرام کے لیے
- دیگر دمہ کی ادویات کے ساتھ اضافی علاج کے طور پر
Kast Tablet 10 mg formula
How to use Kast Tablet 10 mg?
- Take one tablet by mouth once daily in the evening, with or without food
- Swallow the tablet whole with a glass of water
- For exercise induced bronchoconstriction, take the dose at least 2 hours before physical activity
- Do not take an extra dose for exercise if already on a regular daily schedule
- Continue taking it regularly even when asthma symptoms feel controlled
- Do not use it to treat a sudden asthma attack
- Keep taking prescribed inhalers or other asthma medicines unless a doctor advises otherwise
Drug Interactions
- Phenobarbital: Reduces montelukast blood levels by inducing its metabolism, which may lower its effectiveness
- Rifampin: Speeds up montelukast breakdown in the liver and can weaken symptom control
- Gemfibrozil: Raises montelukast blood levels by blocking its metabolism, increasing the chance of side effects
- Other CYP2C8 Inhibitors: May increase montelukast exposure and should be used with medical supervision
- Oral Corticosteroids: Sudden dose reduction while on montelukast has rarely been linked to eosinophilic vasculitis and needs close monitoring
Risks and warnings
- Neuropsychiatric Effects: Mood changes, agitation, sleep disturbances, nightmares and rare suicidal thoughts have been reported and should be discussed with a doctor immediately if they occur
- Not For Acute Attacks: This tablet does not relieve a sudden asthma attack and a fast acting inhaler must be kept available at all times
- Liver Function: Caution is needed in patients with liver impairment since montelukast is metabolized in the liver
- Eosinophilic Conditions: Rare cases of eosinophilic conditions with vasculitis have been reported, usually when oral steroids are reduced at the same time
- Pregnancy And Breastfeeding: Use only if a doctor confirms the benefit outweighs any potential risk to the baby
- Phenylketonuria: Chewable formulations may contain aspartame and should be avoided by patients with phenylketonuria
Kast Tablet 10 mg Side Effects
- Headache
- Stomach pain
- Fatigue or tiredness
- Fever
- Cough
- Dizziness
- Skin rash
- Nausea
- Mood or behavior changes
- Trouble sleeping or vivid dreams
- Upper respiratory tract infection symptoms
Storage Conditions
- Store below 30°C in a cool and dry place
- Keep the tablet in its original blister pack until ready to use
- Protect from moisture, direct sunlight and excess heat
- Keep out of reach of children
- Dispose of expired or unused tablets safely instead of throwing them in household trash