Leflotec Tablet 250mg

About Leflotec Tablet 250mg

Leflotec Tablet 250mg Uses

• Treatment of community acquired pneumonia and acute bronchitis
• Treatment of sinusitis and other upper respiratory tract infections
• Treatment of urinary tract infections and pyelonephritis
• Treatment of skin and soft tissue infections
• Treatment of typhoid fever caused by susceptible bacteria

Leflotec Tablet 250mg Benefits

• Broad spectrum action against many common gram positive and gram negative bacteria
• Once daily dosing improves convenience and adherence to the full course
• Good tissue penetration makes it effective for respiratory and urinary infections
• Available in a tablet form suitable for outpatient treatment of moderate infections

What Experts Say

Levofloxacin works by blocking bacterial DNA gyrase and topoisomerase IV, enzymes that bacteria need to copy their genetic material and multiply. This mechanism gives it activity against a wide range of bacteria responsible for respiratory, urinary, and skin infections, including some organisms that resist older antibiotics.

Prescribers usually choose a five to fourteen day course of Leflotec Tablet 250mg depending on the site and severity of infection, and the dose is reduced in patients with impaired kidney function since the drug is mainly cleared through the kidneys. Completing the full prescribed course, even after symptoms improve, is essential to prevent the bacteria from developing resistance.

Because fluoroquinolones carry a recognized risk of tendon damage and nerve related side effects, physicians in Pakistan generally reserve levofloxacin for infections where safer, narrower spectrum antibiotics are not suitable. Regular review of symptoms and, where needed, kidney function supports safe use of this antibiotic class.

Drug Class

• Fluoroquinolone antibiotic

Leflotec Tablet 250mg formula

• Levofloxacin

Available forms

• Tablet

How to use Leflotec Tablet 250mg?

• Take Leflotec Tablet 250mg exactly as prescribed by your doctor, usually once daily
• Swallow the tablet whole with a full glass of water
• Take it at the same time each day and complete the entire prescribed course
• Avoid taking it with antacids, calcium, or iron supplements within two hours
• Do not skip doses even if symptoms improve before the course ends

Drug Interactions

• Antacids And Mineral Supplements: Calcium, magnesium, iron, and zinc products reduce the absorption of levofloxacin when taken together.
• Warfarin: Levofloxacin can increase the blood thinning effect of warfarin, raising bleeding risk.
• Corticosteroids: Combined use with steroids further increases the risk of tendon rupture.
• QT Prolonging Drugs: Taking levofloxacin with other drugs that affect heart rhythm raises the risk of dangerous arrhythmias.
• Nonsteroidal Anti Inflammatory Drugs: Combining NSAIDs with levofloxacin may raise the risk of central nervous system side effects such as seizures.

Risks and warnings

• Tendon Injury: Levofloxacin can cause tendon inflammation or rupture, especially in older adults and those on steroids.
• Nerve Damage: Peripheral neuropathy with numbness or tingling can occur and may not fully reverse if the drug is not stopped promptly.
• Heart Rhythm Changes: Levofloxacin can prolong the QT interval, raising the risk of irregular heartbeat in susceptible patients.
• Sun Sensitivity: The skin becomes more sensitive to sunlight during treatment, so sun exposure should be limited.
• Not For Children: Levofloxacin is generally avoided in growing children due to effects on developing cartilage, unless specifically advised by a specialist.

Leflotec Tablet 250mg Side Effects

• Nausea and stomach upset
• Diarrhea
• Headache
• Dizziness
• Insomnia
• Sun sensitivity and rash
• Tendon pain or swelling
• Numbness or tingling in the hands and feet
• Irregular heartbeat or palpitations
• Severe allergic reaction with swelling or difficulty breathing

Storage Conditions

• Store Leflotec tablets at room temperature, below 30 degrees Celsius
• Keep the strip inside its original carton away from direct light
• Protect the tablets from moisture and humidity
• Keep the pack out of reach of children
• Discard any unused tablets after completing the prescribed course