Mefo Tablet 250mg

About Mefo Tablet 250mg

Mefo Tablet 250mg Uses

• Relieves moderate menstrual pain and cramps
• Eases pain from osteoarthritis and rheumatoid arthritis
• Reduces pain after minor surgical or dental procedures
• Helps manage acute musculoskeletal pain and sprains
• Used for short term relief of moderate to severe pain

Mefo Tablet 250mg Benefits

• Provides longer lasting pain relief compared to some other NSAIDs
• Reduces both pain and associated inflammation
• Particularly effective for menstrual and gynecological pain
• Available in a convenient tablet form for adults
• Prescribed strength suited for moderate pain that OTC options do not fully control

Mefo Tablet 250mg is prescribed by gynecologists and general physicians across Pakistan for women experiencing painful periods that do not respond well to simple painkillers. Doctors in Lahore, Karachi, Islamabad, and Rawalpindi regularly prescribe mefenamic acid for dysmenorrhea, especially among working women and students who need reliable relief during their monthly cycle. In Karachi, gynecology clinics report frequent prescriptions for menstrual pain linked to fast paced work schedules, while in Lahore and Rawalpindi, orthopedic clinics also use mefenamic acid for joint pain related to arthritis in older patients. Islamabad's clinics see similar demand from office workers with chronic back and joint discomfort. Because Mefo Tablet 250mg requires a prescription in Pakistan, patients are advised to consult a doctor before starting it, particularly for recurring or severe pain rather than occasional discomfort. Pharmacies across these four cities typically stock mefenamic acid brands, making follow up refills straightforward once a doctor has confirmed the diagnosis and dosage.

Mefenamic acid belongs to the fenamate class of nonsteroidal anti inflammatory drugs. Like other NSAIDs, it works by inhibiting cyclooxygenase enzymes, COX-1 and COX-2, which reduces the production of prostaglandins responsible for pain, inflammation, and uterine contractions during menstruation. This is why mefenamic acid is particularly effective for period pain, since it directly reduces the intensity of uterine cramping alongside general pain relief. The tablet typically starts working within 30 to 60 minutes and its effect lasts around 6 hours, which is why it is usually taken two to three times a day during a course of treatment. Compared to some other NSAIDs, mefenamic acid also has a mild additional action on prostaglandin receptors, which may explain why many patients find it especially effective for menstrual and musculoskeletal pain. Because of its potency, it is classified as a prescription medicine in Pakistan rather than an over the counter option.

Mefo Tablet 250mg should be taken exactly as prescribed by a doctor, usually with food to reduce stomach irritation. Treatment for menstrual pain is often started at the onset of bleeding or pain and continued for two to three days, not used as a long term daily medicine. Patients with a history of stomach ulcers, kidney disease, or heart conditions should discuss safer alternatives with their doctor before starting this tablet. It should not be used during the third trimester of pregnancy or while breastfeeding without medical advice. Elderly patients and those on blood pressure or blood thinning medicines need closer monitoring while using mefenamic acid. If pain does not improve within a few days of proper use, or if new symptoms like black stools or severe stomach pain appear, medical attention should be sought immediately rather than continuing the course.

Drug Class

• Nonsteroidal Anti Inflammatory Drug (NSAID)
• Fenamate Class Analgesic
• COX-1 and COX-2 Inhibitor
• Prescription Pain Reliever

Mefo Tablet 250mg formula

• Mefenamic Acid 250mg

Available forms

• Tablet

How to use Mefo Tablet 250mg?

• Take one tablet with food as directed by your doctor, usually two to three times a day.
• Do not use for more than 7 days continuously without medical review.
• Swallow the tablet whole with a full glass of water.
• Take at the first sign of menstrual pain for best effect.
• Follow the exact dose and duration prescribed, do not self adjust.

Drug Interactions

• Aspirin: Combined use increases the risk of gastrointestinal bleeding.
• Anticoagulants: Raises bleeding risk when taken with warfarin or similar blood thinning medicines.
• ACE Inhibitors: Can reduce the blood pressure lowering effect of ACE inhibitor medicines.
• Lithium: May raise lithium levels in the blood, increasing the risk of toxicity.
• Diuretics: Reduces the effectiveness of certain diuretics used for blood pressure or fluid control.

Risks and warnings

• Stomach Bleeding Risk: Long term use raises the risk of ulcers and gastrointestinal bleeding.
• Kidney Caution: Use with care in patients with existing kidney impairment or dehydration.
• Heart Risk: Prolonged high dose use may increase cardiovascular risk in susceptible patients.
• Pregnancy Warning: Avoid during the third trimester of pregnancy due to risk to the baby.
• Diarrhea Risk: Mefenamic acid is more likely than some NSAIDs to cause diarrhea, especially with prolonged use.

Side Effects

• Stomach upset or diarrhea
• Headache
• Drowsiness
• Skin rash in some patients

• Signs of stomach bleeding such as black stools
• Severe allergic reaction with swelling or breathing trouble
• Unusual bruising or bleeding
• Reduced urine output suggesting kidney trouble

Storage Conditions

Store below 30 degrees Celsius in a cool, dry place away from moisture and direct sunlight. Keep the tablet strip inside its original packaging until use. Keep out of reach of children. Do not use after the expiry date printed on the pack.