Protan Tablet 250mg

About Protan Tablet 250mg

Protan Tablet 250mg Uses

• Menstrual pain and cramps
• Headache and migraine related pain
• Toothache and pain after dental procedures
• Mild to moderate joint and muscle pain
• Fever linked with minor infections

What Experts Say

Mefenamic acid belongs to the fenamate group within the broader NSAID family. It works by blocking cyclooxygenase enzymes, which lowers the production of prostaglandins, the chemical messengers responsible for pain, swelling, and fever. This mechanism gives fast relief for cramping and inflammatory pain, which is why it remains a common first choice for period pain.

Clinical guidance generally limits mefenamic acid to short courses, often five to seven days, since prolonged NSAID use raises the risk of stomach irritation, ulcers, and reduced kidney blood flow. Taking the tablet with food or milk is a standard recommendation to protect the stomach lining during treatment.

This medicine is usually avoided during the third trimester of pregnancy, in people with active peptic ulcers, and in those with significant kidney or heart disease. Anyone taking blood thinners, other NSAIDs, or long term steroids should discuss the combination with a doctor before starting mefenamic acid, since the interaction can raise bleeding or stomach risk.

Drug Class

• Nonsteroidal anti-inflammatory drug (NSAID), fenamate group

Protan Tablet 250mg formula

• Mefenamic Acid 250mg

Available forms

• Tablet

How to use Protan Tablet 250mg?

• Take one Protan 250mg tablet with a meal or a glass of milk to reduce stomach upset.
• Do not exceed the dose or duration your doctor has prescribed.
• Swallow the tablet whole with water, do not crush or chew it.
• Most short term pain relief courses last no longer than seven days unless a doctor advises otherwise.
• If a dose is missed, take it as soon as remembered unless the next dose is close.

Drug Interactions

• Blood thinners (Warfarin): Increases the risk of bleeding when combined.
• Other NSAIDs or Aspirin: Raises the risk of stomach ulcers and bleeding.
• ACE inhibitors or ARBs: Mefenamic acid can reduce their blood pressure lowering effect and affect kidney function.
• Diuretics: Combined use may reduce the diuretic effect and strain the kidneys.
• Lithium: Can raise lithium levels to potentially toxic amounts.
• Corticosteroids: Increases the risk of stomach irritation and bleeding.

Risks and warnings

• Stomach irritation: Can cause ulcers or bleeding, especially with long term or high dose use.
• Kidney function: Use with caution in people with existing kidney disease or dehydration.
• Pregnancy: Avoid in the third trimester, since NSAIDs can affect the baby's heart and reduce amniotic fluid.
• Heart risk: Long term or high dose NSAID use may raise the risk of heart attack or stroke.
• Allergy: Avoid if you have had an allergic reaction to aspirin or other NSAIDs, including asthma triggered by these medicines.
• Bleeding risk: Use cautiously with blood thinners or a history of bleeding disorders.

Protan Tablet 250mg Side Effects

Most people tolerate mefenamic acid well for short term use, though some effects can occur.

• Stomach pain or indigestion
• Nausea or vomiting
• Diarrhea
• Headache
• Dizziness
• Drowsiness
• Skin rash
• Black or bloody stools: seek immediate medical care, as this can signal stomach bleeding.

Storage Conditions

Store below 30°C in a cool, dry place, away from moisture and direct sunlight. Keep out of reach of children.