Meronem Inj 1g

Meronem Inj Uses

Meronem injection is an antibiotic medication that is used to treat bacterial infections. It is composed of Meropenem which belongs to the carbapenem antibiotics class of medications. They work by inhibiting the synthesis of the cell wall of bacteria, hence making it difficult for them to survive. Antibiotics can only fight against bacteria. They are not active against viruses. Therefore, they are only given to treat bacterial infections.

Meronem Inj 1g formula

• Meropenem

Available forms

• Injection

Risks and warnings

Generally, Meronem injection is well tolerated. However, you should know its risks and warnings so that you do not take it when the risk is greater than the benefit.

When your healthcare provider prescribes you any medication, they do so based on the risk versus benefit ratio. Therefore you should give a complete medication and medical history to your healthcare provider. In this way, you can avoid the adverse effects of certain medications.

The risks and warnings associated with Meronem injection are:

Allergic to Meropenem

If you are allergic to carbapenems, do not take Meropenem or any other medicine with the same generic name, as it can result in a life-threatening condition called anaphylactic shock.

Always inform your healthcare provider about the documented allergies you have. 

Non-susceptible organisms

Meropenem should be given to the patient only when the bacteria are sensitive to it. If not, it can lead to antibiotic resistance, making it difficult to treat infections next time. It mostly applies to urinary tract infections and infections of the nose, ear, and throat.

Seizures 

If you have had a history of seizures or you have renal impairment, you must avoid the use of Meropenem as it can provoke seizures.

Kidney failure

If your kidneys do not work well, the healthcare provider may lower the dose of the drug. It happens because your kidneys are meant to excrete out the waste and toxins. If that does not happen, the toxins may build up in your body, leading to severe adverse effects. Therefore, you must inform your health care provider about your complete health condition.

Jarisch-Herxheimer reaction

Jarisch-Herxheimer's reaction happens when Meropenem is given to the patient with Lyme disease. It happens because of the release of endotoxins due to the death of bacteria. 

Liver diseases

Patients with liver disease should take Meropenem with caution. It is because your liver helps in the metabolism and excretion of drugs. When it does not work efficiently due to any disease, it can cause accumulation of the drug in your body, leading to severe adverse effects. 

Pregnancy and breastfeeding

If you are pregnant, do not take Meropenem unless your doctor advises it. It can affect your baby’s health. Breastfeeding mothers should also consult with a healthcare provider before taking it. 

Anticoagulants or bleeding disorders

If you are taking anticoagulants for thinning of your blood, or you have any bleeding disorder, take Meropenem only on the advice of a healthcare provider.

How to use Meronem Inj 1g?

• The injection should be administered by or under the supervision of a health care professional
• Meropenem is injected intravenously. The healthcare providers will dilute the powder in sterile water and form a solution. After that, they will mix it in normal saline or some other solution and will infuse it over 30 minutes
• The frequency and dosage depends on your symptoms and response to the treatment
• Do not use it after the expiration date

Meronem Inj Side Effects

The common side effects of Meronem injection are:

• Abdominal pain 
• Vomit containing coffee grounds 
• Blood in stool 
• Constipation 
• Black stools 
• Acid reflux
• Anemia 
• Elevation of liver enzymes
• Diarrhea 
• Serum sickness 
• Risk of infections
• Crystalluria 
• Eye discomfort
• Gastric discomfort
• Lethargy and body pain
• Headache 
• Hearing impairment
• Nausea
• Pancreatitis 
• Sleep disorders
• Vision disorders 
• Altered taste
• Pain at the injection site

Drug Interactions

Meronem injection can interact with the following medications:

• Probenecid
• Blood thinners like warfarin 
• Allopurinol 
• Oral birth control pills containing estrogen and progesterone.
• Other antibiotics like chloramphenicol, tetracyclines, sulfonamides, and macrolides.
• Cholesterol-lowering drugs like atorvastatin, rosuvastatin, and other statins.
• Ergot alkaloids
• Colchicine 
• Oral hypoglycemicagents like repaglinide, rosiglitazone, nateglinide, and pioglitazone
• Quetiapine 
• Antiarrhythmic drugs like amiodarone and procainamide
• Benzodiazipine like diazepam, midazolam and triazolam 
• Calcium containing supplements
• Iron supplements
• Zinc and bismuth-containing drugs

Storage Conditions

• Store the medicine at room temperature
• Keep out of reach and sight of children
• Protect it from sunlight and moisture