Quick facts

  • Pain due to arthritis and osteoarthritis
  • Menstrual cramps
  • Joint pain
  • Migraine
  • Pain associated with gout
  • Muscle spasm
  • Bone pain
  • Ankylosing spondylitis
  • Tendonitis
  • Sprains
  • Pain associated with fractures
  • Back pain
  • Pain due to frozen shoulder
  • Neck pain
  • Bursitis

Nuberol Tablet 35mg/450mg

by Searle

Nuberol is a combination of paracetamol and orphenadrine citrate, a pain reliever, and a muscle relaxant.

Rs. 572.27
Rs. 572.27

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Table of contents

Nuberol Uses

Nuberol is used for the treatment of pain or muscle spasms due to multiple sclerosis or spinal cord injury or disease. It is used to treat rheumatological conditions, orthopedic and traumatic disorders. Moreover, it helps gain muscle tone and reduces soreness and stiffness.

Nuberol Tablet 35mg/450mg formula

  • Orphenadrine
  • Paracetamol

Available forms

  • Tablets

Risks and warnings

You should know the risks and warnings of Nuberol to prevent its misuse.

There are some specific circumstances under which the use of certain medications is contraindicated or considered dangerous. So if you are taking any medicine its always a good practice to familiarize yourself with its risks and warnings.

The risks and warnings associated with Nuberol are:

1. Allergic to Paracetamol or Orphenadrine Citrate

If you are allergic to paracetamol or orphenadrine citrate, do not take Nuberol or any other medicine with the same generic name, as it can result in a life-threatening condition called anaphylactic shock.

2. Skin reaction

If you ever have had a skin reaction known as Steven Johnson syndrome upon Paracetamol intake, do not take Nuberol. Tell your healthcare provider your complete medical history. 

3. Alcohol intake

If you drink more than three glasses of alcohol in a day, take paracetamol with caution as it increases the chances of liver damage.

If you drink alcohol, discuss it with a healthcare provider before taking Orphenadrine Citrate, as it can make you feel dizzy.

4. Glucose 6 phosphate dehydrogenase deficiency

Patients who have a condition called glucose 6 phosphate dehydrogenase deficiency, must take Nuberol with extreme caution as it can cause hemolysis.

5. Malnutrition

People suffering from long-term malnutrition must take paracetamol with caution.

6. Asthma

If you are asthmatic, take Nuberol with caution.

7. Low blood pressure

If you have a history of low blood pressure or if you are taking medicines to control high blood pressure, you must take orphenadrine citrate with caution.

8. Kidney disease

If you have kidney disease, take orphenadrine citrate with caution as it can worsen the preexisting condition. Do not forget to tell your healthcare provider about it.

9. Liver diseases

Patients with liver disease should take Nuberol with caution. It is because your liver helps in the metabolism and excretion of drugs. When it does not work properly due to any disease, it can cause accumulation of the drug in your body, leading to severe adverse effects.

10. Sedatives

If you are already taking sedatives or sleeping aids, take Nuberol with caution as orphenadrine can make you feel dizzy.

11. Pregnancy and breastfeeding

If you are pregnant, do not take Nuberol unless your doctor advises it. It can affect the health of your baby. Breastfeeding mothers should also consult with a healthcare provider before taking it.

12. Operating machinery

Do not drive a car or operate any machinery while you take Nuberol, as it can cause sedation, which can eventually lead to accidents.

How to use Nuberol Tablet 35mg/450mg?

  • Take Nuberol tablet with a glass of water and swallow it whole. Follow the instructions given by your doctor.
  • Do not use Nuberol after the mentioned expiry date.
  • It is better to take it with food. But you can also take it on an empty stomach.
  • Nuberol should be taken as prescribed by your healthcare provider. Mostly it is prescribed twice or thrice a day.

Nuberol Side Effects

Patients taking Nuberol may experience any of the following side effects:

  • Shortness of breath
  • Rashes
  • Swelling
  • Dizziness
  • Hives
  • Decreased white blood cells
  • Decreased red blood cells
  • Decreased platelets
  • Cough
  • Disorientation
  • Arrhythmia
  • Dizziness
  • Dry mouth
  • Fatigue
  • Hypotension
  • Sleepiness
  • Drowsiness
  • Nausea
  • Vomiting
  • Dry eyes
  • Nasal congestion

Drug Interactions

Nuberol may interact with the following drugs. A drug interaction does not mean that you stop taking the medicine on your own. But, you must tell your healthcare provider about it.

  • Lomitapide
  • Tetracaine
  • Warfarin
  • Flibanserin
  • Imatinib
  • Isoniazid
  • Axitinib
  • Mipomersen
  • Busulfan
  • Dapsone topical
  • Eltrombopag
  • Exenatide injectable solution and suspension
  • Ivacaftor
  • Daclizumab
  • Lixisenatide
  • Propoxyphene

To avoid drug interactions, you must give a complete history to the healthcare provider about other health conditions you have and what medicines you have been taking. At times, a dose adjustment can help prevent drug interaction.

Storage Conditions

  • Keep the product out of the reach and sight of children.
  • Store it at room temperature.
  • Do not use it after the mentioned expiry date.


Frequently Asked Questions

What is the price of Nuberol Tablet 35mg/450mg in Pakistan?

The Nuberol Tablet 35mg/450mg price in Pakistan is Rs. 572.27

What is Nuberol Tablet 35mg/450mg used for?

Nuberol Tablet 35mg/450mg is used in the following conditions:
  • Pain due to arthritis and osteoarthritis
  • Menstrual cramps
  • Joint pain
  • Migraine
  • Pain associated with gout
  • Muscle spasm
  • Bone pain
  • Ankylosing spondylitis
  • Tendonitis
  • Sprains
  • Pain associated with fractures
  • Back pain
  • Pain due to frozen shoulder
  • Neck pain
  • Bursitis

What is Nuberol Tablet 35mg/450mg composed of?

Nuberol Tablet 35mg/450mg is composed of:
  • Orphenadrine
  • Paracetamol

Do you need a prescription to buy Nuberol Tablet 35mg/450mg?

To buy Nuberol Tablet 35mg/450mg you must have a prescription signed by your doctor.


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