Oscal D Tablet 0.25mcg / 200mg

About Oscal D Tablet 0.25mcg / 200mg

Oscal D Tablet 0.25mcg / 200mg Uses

• Renal osteodystrophy (bone disease caused by chronic kidney disease)
• Hypoparathyroidism and secondary hyperparathyroidism
• Vitamin D deficiency with low blood calcium
• Rickets in children and osteomalacia in adults
• Osteoporosis management alongside other therapy

Oscal D Tablet 0.25mcg / 200mg Benefits

• Combines an active vitamin D analog with calcium in a single tablet
• Does not require kidney activation, useful for patients with reduced kidney function
• Supports bone mineralization and helps prevent fractures
• Convenient once daily dosing improves treatment adherence

What Experts Say

Physicians across Pakistan often favor alfacalcidol over standard vitamin D3 in patients with reduced kidney function, because it does not require renal activation to become effective, unlike cholecalciferol, which depends on healthy kidney function for conversion into its active form.

Doctors monitor serum calcium and phosphate levels regularly during alfacalcidol therapy, since this active vitamin D analog raises the risk of hypercalcemia more than inactive vitamin D forms do. Dose adjustments are common after routine blood work in patients with chronic kidney disease.

Clinical guidance favors starting at a low dose in elderly patients and those with reduced kidney function, then titrating upward gradually based on the calcium response seen on follow up blood tests. Physicians also recommend adequate fluid intake to lower the risk of kidney stone formation during long term calcium and vitamin D therapy.

Drug Class

• Vitamin D Analogs and Calcium Supplements

Oscal D Tablet 0.25mcg / 200mg formula

• Alfacalcidol + Calcium Carbonate

Available forms

• Tablet

How to use Oscal D Tablet 0.25mcg / 200mg?

• Take Oscal D tablet once daily or as directed by your doctor
• Swallow the tablet whole with a glass of water, preferably with a meal
• Take at the same time each day to maintain steady blood calcium levels
• Do not take double doses to make up for a missed dose
• Get periodic blood tests for calcium and kidney function as advised by your doctor

Drug Interactions

• Thiazide Diuretics: Combined use can increase the risk of hypercalcemia by reducing calcium excretion.
• Digoxin: High calcium levels can increase the risk of digoxin toxicity and abnormal heart rhythm.
• Magnesium Containing Antacids: Calcium carbonate may reduce absorption of certain medicines if taken together, separate dosing is advised.
• Corticosteroids: Steroids can reduce calcium absorption, requiring dose review with a doctor.
• Iron Supplements: Calcium carbonate can reduce iron absorption, so doses should be spaced a few hours apart.

Risks and warnings

• Hypercalcemia Risk: This medicine can raise blood calcium too high, causing nausea, weakness, and confusion if untreated.
• Kidney Stones: Long term use with inadequate fluid intake may increase the risk of kidney stone formation.
• Kidney Disease: Dose should be adjusted carefully in patients with significant renal impairment under medical supervision.
• Heart Conditions: Use cautiously in patients on digoxin or with heart disease, since high calcium can affect heart rhythm.
• Pregnancy: Use only under medical supervision, as excess calcium and vitamin D intake should be monitored during pregnancy.

Oscal D Tablet 0.25mcg / 200mg Side Effects

• Nausea and stomach upset
• Constipation
• Headache
• Dry mouth
• Loss of appetite
• Excessive thirst
• Weakness or fatigue if calcium levels rise too high
• Metallic taste
• Bloating

Storage Conditions

• Store at room temperature below 30°C in a dry place
• Keep the tablet strip in its original packaging away from light
• Keep away from moisture, do not store in the bathroom
• Keep out of reach of children