Prezone Injection 1gm

About Prezone Injection 1gm

Prezone Injection 1gm Uses

• Treatment of community acquired and hospital acquired pneumonia
• Management of typhoid fever, including drug resistant strains common in Pakistan
• Treatment of bacterial meningitis
• Treatment of complicated urinary tract infections
• Treatment of skin, soft tissue, and bone infections caused by susceptible bacteria

Prezone Injection 1gm Benefits

• Broad activity against many types of bacteria with just one dose a day
• High blood and tissue levels that help fight severe infections quickly
• Shorter hospital stays when this injection is started early in serious infections
• Suitable for both intravenous and intramuscular administration depending on the clinical setting
• Effective against many bacteria that have become resistant to older antibiotics

Prezone Injection 1gm is available at hospital pharmacies and major retail pharmacies across Lahore, Karachi, Islamabad, and Rawalpindi, making it accessible for patients who need urgent antibiotic treatment. Patients in these cities can also book a same day consultation with a physician through oladoc before starting this injection.

Pakistan has one of the highest rates of extensively drug resistant typhoid in the world, and ceftriaxone remains one of the few injectable antibiotics that still works reliably against it. This is why doctors often prefer this injection once resistant typhoid is suspected.

This injection should only be given under the supervision of a qualified doctor or in a hospital setting, since dosing depends on the infection type, patient weight, and kidney function. A missed or incomplete course can allow bacteria to survive and become harder to treat.

Drug Class

• Third generation cephalosporin antibiotic
• Beta lactam class of antibacterial drugs
• Bactericidal action that stops bacteria from building their protective cell wall

Prezone Injection 1gm formula

• Ceftriaxone Sodium

Available forms

• Injection

How to use Prezone Injection 1gm?

• This injection is given by a trained healthcare provider through a vein or into a muscle, never at home without medical supervision.
• The usual adult dose ranges from 1 gram to 2 grams once daily, depending on the severity and type of infection.
• A full course should be completed exactly as prescribed, even if symptoms improve within a few days.
• Blood tests may be requested by the doctor during longer courses to check kidney and liver function.

Drug Interactions

This injection can interact with certain other medicines, so patients should share a complete list of current medications with their doctor before starting treatment.

• Calcium containing IV products: Calcium containing IV solutions used together with this injection in newborns have caused fatal reactions, and this combination must be avoided.
• Warfarin: This injection can increase the blood thinning effect of warfarin and raise bleeding risk.
• Aminoglycoside antibiotics: Aminoglycoside antibiotics such as gentamicin combined with this injection may increase the risk of kidney related side effects.
• Oral contraceptives: Antibiotic use during a course of this injection may reduce the reliability of birth control pills, so a backup method is advised.

Risks and warnings

• Allergy history: Patients with a known allergy to penicillin or other cephalosporins face a higher chance of a cross reaction with this injection.
• Kidney or liver disease: Dose adjustment may be needed in patients with significant kidney or liver impairment.
• Newborns: This injection is generally avoided in newborns, especially those with jaundice, due to a risk of a serious condition called kernicterus.
• Pregnancy and breastfeeding: This injection should only be used in pregnancy or while breastfeeding if a doctor decides the benefit outweighs the risk.
• Gallbladder concerns: Rare cases of gallbladder sludge or stones have been reported with this medicine, usually reversible after stopping treatment.

Side Effects

Most people tolerate this injection well, though some mild reactions can occur at the injection site or in the digestive system.

• Pain, redness, or swelling at the injection site
• Nausea or mild stomach upset
• Diarrhea
• Headache
• Rash or mild itching

A small number of patients experience more serious reactions that need immediate medical attention.

• Severe allergic reaction with swelling of the face, lips, or throat
• Difficulty breathing or wheezing
• Severe or bloody diarrhea, which can signal a serious intestinal infection
• Yellowing of the skin or eyes, a possible sign of liver or gallbladder problems

Storage Conditions

Store this injection vial in a cool, dry place below 25°C, away from direct sunlight. Keep the reconstituted solution refrigerated and use it within the time specified by the pharmacist. Keep out of reach of children.