About Progrel Tablet 75mg
Clopidogrel Bisulphate 75mg is an antiplatelet medicine used to prevent blood clots in heart attack and stroke risk.
Progrel Tablet 75mg Uses
- Prevents blood clots after a recent heart attack (myocardial infarction)
- Reduces stroke risk in people with a history of stroke or mini stroke (TIA)
- Prevents clot formation after coronary stent placement, often combined with aspirin
- Manages peripheral arterial disease to improve blood flow in the legs
- Used in acute coronary syndrome, including unstable angina and non ST elevation heart attack
Progrel Tablet 75mg Benefits
- Lowers the chance of a second heart attack or stroke in high risk patients
- Keeps blood flowing smoothly through narrowed or stented arteries
- Works well alongside aspirin for short term dual antiplatelet therapy after stenting
- Convenient once daily dosing improves long term adherence
- Widely studied with a well established safety profile in cardiovascular care
Drug Class
- Antiplatelet agent
- P2Y12 receptor blocker
- Thienopyridine derivative
What Experts Say
Cardiologists prescribe Clopidogrel Bisulphate to patients recovering from a heart attack or ischemic stroke because it blocks platelets from clumping together. This lowers the chance of a new clot forming inside a narrowed or stented artery. For patients who have just received a coronary stent, this protection matters most in the first few months.
Doctors often pair Clopidogrel with low dose aspirin for a set period after a cardiac event or procedure, known as dual antiplatelet therapy. This combination lowers cardiovascular risk more than either drug alone, though it also raises bleeding risk, so specialists weigh this before extending treatment beyond the recommended duration.
Response to Clopidogrel can vary because the liver must convert it into its active form, and some people process it more slowly. Physicians may check for interacting medicines, particularly certain acid reducing drugs, before starting long term therapy. Regular follow up confirms the medicine is protecting the heart without causing unwanted bleeding.
Progrel Tablet 75mg Uses in Urdu
- دل کے دورے کے بعد خون کے لوتھڑے بننے سے روکنے کے لیے
- فالج یا منی اسٹروک کا خطرہ کم کرنے کے لیے
- دل کی شریان میں اسٹینٹ لگنے کے بعد بلڈ کلاٹ سے بچاؤ کے لیے
- ٹانگوں کی شریانوں میں خون کی روانی بہتر بنانے کے لیے
Progrel Tablet 75mg formula
- Clopidogrel Bisulphate 75mg
How to use Progrel Tablet 75mg?
- Take Progrel Tablet 75mg once daily, at the same time each day
- Swallow the tablet whole with a glass of water
- Take with or without food, though food may reduce stomach upset
- Do not crush or chew the tablet
- Continue taking it for the full duration your doctor prescribes, even if you feel well
- Do not stop the medicine suddenly without consulting your doctor, especially after a recent stent
Drug Interactions
- Aspirin: Increases bleeding risk when combined, though often prescribed together short term under medical supervision
- Omeprazole And Esomeprazole: May reduce how well Clopidogrel is activated in the liver, lowering its protective effect
- Warfarin And Other Blood Thinners: Combined use significantly raises bleeding risk
- NSAIDs: Painkillers like ibuprofen or diclofenac add to the bleeding risk when used regularly
- SSRIs And SNRIs: Certain antidepressants may further increase bleeding tendency
Risks and warnings
- Active Bleeding: Avoid use if you have a peptic ulcer, active bleeding, or a recent major injury
- Upcoming Surgery: Inform your surgeon and dentist in advance, since Clopidogrel is usually stopped five to seven days before elective surgery
- Bruising And Bleeding: Report unusual bruising, nosebleeds, blood in urine or stool, or prolonged bleeding from cuts
- Liver Or Kidney Disease: Use with caution and closer monitoring in people with significant liver or kidney impairment
- Pregnancy And Breastfeeding: Use only if your doctor confirms the benefit outweighs the risk
- Poor Metabolizers: Some people convert Clopidogrel less efficiently in the liver, which may reduce its protective effect
Progrel Tablet 75mg Side Effects
- Easy bruising
- Nosebleeds
- Indigestion or stomach upset
- Diarrhea
- Headache
- Dizziness
- Skin rash or itching
- Prolonged bleeding from minor cuts
- Blood in urine or stool (seek immediate care)
- Severe or uncontrolled bleeding (seek immediate care)
- Signs of stroke such as sudden weakness or slurred speech (seek immediate care)
- Unexplained fever with weakness, a possible sign of a rare blood disorder called thrombotic thrombocytopenic purpura
Storage Conditions
- Store below 30°C in a cool, dry place
- Keep the strip in its original blister pack until you are ready to take a dose
- Protect from direct sunlight and moisture
- Keep out of reach of children
- Do not use beyond the expiry date printed on the pack