Rabipur Injection 2.5IU

About Rabipur Injection 2.5IU

Rabipur Injection 2.5IU Uses

• Post exposure prophylaxis after an animal bite or scratch, especially from a dog, cat, or stray animal common in Pakistan
• Pre exposure prophylaxis for vets, animal handlers, and travelers to high risk rabies areas
• Prevention of rabies infection when given promptly after suspected exposure
• Part of the WHO recommended rabies immunization schedule used in government and private hospitals across Pakistan

Rabipur Injection 2.5IU Benefits

• Highly effective at preventing rabies when started before symptoms appear
• Purified chick embryo cell technology gives a strong immune response with fewer reactions than older nerve tissue vaccines
• Can be combined with rabies immunoglobulin for category III bites for added protection
• Widely available and used in Lahore, Karachi, Islamabad, and Rawalpindi hospitals for emergency bite management

What Experts Say

Rabipur belongs to a class of vaccines called inactivated cell culture rabies vaccines. It contains a killed form of the rabies virus grown on purified chick embryo cells, so it cannot cause rabies itself. Once injected, it trains the immune system to recognize the virus and build protective antibodies before a live rabies infection can take hold.

In Pakistan, dog bites are one of the most common reasons families visit the emergency department, and rabies is almost always fatal once symptoms begin. That is why doctors treat any bite or scratch from a stray dog, cat, or monkey as a medical emergency and start this vaccine as soon as possible, ideally on the same day.

For a fresh bite, the vaccine is usually given on days 0, 3, 7, and 14 into the arm muscle, sometimes with rabies immunoglobulin injected around the wound for deeper or more severe bites. Missing a scheduled dose can weaken the protection, so clinics in Lahore, Karachi, Islamabad, and Rawalpindi usually keep a record and call patients to remind them of follow up visits.

Drug Class

• Inactivated viral vaccine
• Rabies immunoprophylaxis agent
• Purified chick embryo cell culture vaccine

Rabipur Injection 2.5IU formula

• Purified Chick Embryo Cell Rabies Vaccine (Inactivated) 2.5IU

Available forms

• Injection

How to use Rabipur Injection 2.5IU?

• Complete the full vaccination schedule of 4 doses on days 0, 3, 7, and 14 as advised by your doctor after a bite or scratch
• Report to the nearest hospital or vaccination center in Lahore, Karachi, Islamabad, or Rawalpindi within 24 hours of an animal bite for the first dose
• Clean the wound thoroughly with soap and running water for at least 15 minutes before the injection is given
• Inform your doctor if you have had a rabies vaccine before or if you are taking chloroquine for malaria prevention
• Do not stop the vaccination course early even if the biting animal appears healthy, unless a doctor confirms it is safe to stop

Drug Interactions

• Chloroquine and Antimalarials: These medicines can lower the antibody response to Rabipur, so doctors may adjust the injection route or add extra monitoring.
• Corticosteroids and Immunosuppressants: Long term steroid or immunosuppressant use can blunt the immune response, sometimes requiring antibody level testing after vaccination.
• Other Live Vaccines: Rabipur can generally be given alongside other vaccines, but doctors usually use separate injection sites and syringes.
• Rabies Immunoglobulin: When given for severe bites, immunoglobulin should be injected at a different site from Rabipur to avoid reducing the vaccine's effect.

Risks and warnings

• Incomplete Course: Stopping the vaccine schedule before all doses are given can leave you unprotected against rabies.
• Immunosuppression: People on chemotherapy, high dose steroids, or with HIV may develop a weaker antibody response and may need extra doses or antibody testing.
• Allergic Reaction: Rare but serious allergic reactions can occur, so vaccination should be given at a facility equipped to manage them.
• Chloroquine Use: Antimalarial chloroquine can reduce the immune response to this vaccine, so the intramuscular route and full dosing schedule should be followed carefully.
• Delayed Vaccination: Waiting too long after a bite reduces how well the vaccine can prevent rabies, so early administration is critical.

Rabipur Injection 2.5IU Side Effects

• Pain, redness, or swelling at the injection site
• Mild fever
• Headache
• Body aches and fatigue
• Nausea
• Dizziness
• Swollen lymph nodes near the injection site
• Rarely, an allergic skin rash

Storage Conditions

• Store in a refrigerator between 2°C and 8°C, never in the freezer
• Keep the vial in its original carton to protect it from light
• Use the vaccine promptly after reconstitution as advised by the healthcare provider
• Keep out of reach of children and away from direct heat