Repar Tablet 20mg

About Repar Tablet 20mg

Repar Tablet 20mg Uses

• Treatment of active duodenal ulcers
• Healing of erosive or ulcerative gastroesophageal reflux disease (GERD)
• Long term maintenance of GERD symptom control
• Symptomatic relief of moderate to severe heartburn
• Combination therapy for Helicobacter pylori eradication
• Management of pathological hypersecretory conditions such as Zollinger Ellison syndrome

Repar Tablet 20mg Benefits

• Fast acting relief from acid related pain within days of starting therapy
• Delayed release coating protects the drug until it reaches the intestine
• Once daily dosing improves treatment adherence
• Effective acid suppression supports faster ulcer healing
• Reduces risk of ulcer recurrence with continued, correctly timed use

What Experts Say

Rabeprazole is a proton pump inhibitor that binds irreversibly to the hydrogen potassium ATPase enzyme in gastric parietal cells. This blocks the final step of acid secretion no matter what triggers it, and because rabeprazole converts to its active form quickly in an acidic environment, its onset of acid suppression is often faster than several other PPIs.

Gastroenterologists commonly prescribe the 20mg strength for duodenal ulcer healing, which is typically achieved within four weeks in most patients, and for long term control of gastroesophageal reflux disease. It is also included in standard triple therapy regimens with antibiotics for Helicobacter pylori eradication, a common cause of ulcers seen in Pakistani patients.

Physicians recommend using the lowest effective dose for the shortest necessary duration once symptoms are controlled. Patients with liver impairment or those on long term therapy should have periodic review, since prolonged acid suppression can affect nutrient absorption and bone health over time.

Drug Class

• Proton Pump Inhibitor (PPI)

Repar Tablet 20mg formula

• Rabeprazole

Available forms

• Tablet

How to use Repar Tablet 20mg?

• Take one tablet daily before breakfast, at the same time each day
• Swallow the tablet whole with a glass of water
• Do not crush, break, or chew the tablet
• Complete the full prescribed course even if symptoms ease early
• Take alongside antibiotics exactly as directed when used for H. pylori treatment

Drug Interactions

• Clopidogrel: May reduce clopidogrel effectiveness, increasing cardiovascular risk.
• Methotrexate: High dose methotrexate levels may rise, increasing toxicity risk.
• Warfarin: May affect INR and increase bleeding risk with concurrent use.
• Atazanavir: Absorption of this antiretroviral drug is reduced by acid suppression.
• Digoxin: Increased absorption may raise the risk of digoxin toxicity.
• Ketoconazole and Itraconazole: Reduced absorption of these antifungal drugs due to lower stomach acidity.

Risks and warnings

• Bone Fracture Risk: Long term use may raise the chance of hip, wrist, or spine fractures in older adults.
• Vitamin B12 Deficiency: Extended therapy can lower B12 absorption over time.
• Magnesium Levels: Long term use may cause low magnesium, leading to cramps or irregular heartbeat.
• Kidney Concerns: Rare cases of acute interstitial nephritis have been reported with prolonged use.
• Liver Impairment: Use with caution and closer monitoring in patients with severe liver disease.
• Pregnancy and Breastfeeding: Use only when clearly needed and under medical supervision.

Repar Tablet 20mg Side Effects

• Headache
• Nausea
• Abdominal pain
• Diarrhea or constipation
• Flatulence
• Dry mouth
• Dizziness
• Rash
• Signs of low magnesium such as muscle cramps or irregular heartbeat
• Severe allergic reaction with facial swelling or difficulty breathing
• Persistent watery diarrhea suggesting intestinal infection

Storage Conditions

• Store below 30°C in a cool, dry place
• Keep tablets in the original blister strip until use
• Protect from moisture and direct sunlight
• Keep out of reach of children
• Discard any unused tablets after the expiry date