RIFINAH tablet 450mg

About RIFINAH tablet 450mg

RIFINAH tablet 450mg Uses

• Treatment of tuberculosis (TB)
• Continuation phase of TB therapy
• Combining two anti-TB medicines in one tablet
• Preventing TB drug resistance when used correctly

Drug Class

• Antitubercular combination
• Rifampicin plus isoniazid

What Experts Say

Rifampicin and isoniazid are two of the core medicines used to cure tuberculosis. Combining them in one tablet attacks the bacteria in different ways, which is more effective and helps prevent the TB germ from becoming resistant.

TB treatment is long, usually several months, and must be completed exactly as prescribed even after the patient feels well. Stopping early is the main reason TB returns and becomes drug resistant.

These medicines can affect the liver, so doctors monitor liver function and advise patients to report yellowing of the eyes, nausea or dark urine. Rifampicin also turns urine, sweat and tears a harmless orange-red colour.

RIFINAH tablet 450mg formula

• Rifampicin 450mg
• Isoniazid 300mg

Available forms

• Tablet

How to use RIFINAH tablet 450mg?

• Take once daily on an empty stomach, an hour before food, as prescribed.
• Swallow with water at the same time each day.
• Complete the entire TB course even after you feel well.
• Do not miss doses; missed doses reduce the cure and raise resistance.
• Attend all follow up and liver function checks.

Drug Interactions

Rifampicin strongly speeds the breakdown of many medicines, reducing their effect.

• Combined hormonal contraceptives: Reliability is reduced; use another method.
• Warfarin: Its blood thinning effect is reduced.
• Many other medicines: Rifampicin can lower levels of numerous drugs; share your full list.
• Alcohol: Increases the risk of liver harm with isoniazid.

Risks and warnings

• Liver health: Can affect the liver; report yellow eyes, nausea or dark urine.
• Complete the course: Stopping early causes relapse and drug resistance.
• Orange-red body fluids: Rifampicin harmlessly colours urine, sweat and tears.
• Nerve effects: Isoniazid can affect nerves; vitamin B6 is often added.
• Many interactions: Rifampicin lowers the effect of several medicines.

RIFINAH tablet 450mg Side Effects

• Nausea
• Loss of appetite
• Orange-red urine and tears (harmless)
• Tingling in hands or feet
• Rarely, raised liver enzymes

Storage Conditions

Store below 30°C in a dry place away from moisture and direct sunlight, out of reach of children.