Symbidow capsule 400mcg / 12mcg

About Symbidow capsule 400mcg / 12mcg

Symbidow Capsule Uses

• Regular maintenance treatment of asthma in adults and adolescents
• Long term management of chronic obstructive pulmonary disease, or COPD
• Reducing frequent asthma flare ups when other inhalers are not enough
• Improving day to day breathing in patients with persistent symptoms
• Add on therapy alongside a reliever inhaler for uncontrolled asthma

Symbidow Capsule Benefits

• Combines an anti inflammatory steroid with a long acting bronchodilator in one device
• Reduces airway inflammation that drives asthma and COPD symptoms
• Keeps airways open for extended relief between doses
• Can reduce the frequency of asthma or COPD flare ups with regular use

What Experts Say

Budesonide is an inhaled corticosteroid that reduces swelling and mucus production in the airways, while formoterol is a long acting beta agonist that relaxes the muscles around the airways to keep them open. Together they address both the inflammation and the narrowing that cause breathing symptoms.

Symbidow is delivered through the Dowhaler, a dry powder inhaler device, rather than swallowed like an ordinary capsule. Pulmonologists in Pakistan stress correct inhaler technique, since poor technique is one of the most common reasons inhaled therapy does not work as expected.

Mouth rinsing after each dose helps prevent oral thrush, a fungal infection that can develop from inhaled steroids settling in the mouth and throat. This medicine is used regularly as prescribed rather than only during flare ups, since it works best as a preventive maintenance treatment and does not relieve a sudden attack.

Drug Class

• Inhaled Corticosteroid and Long Acting Beta Agonist (ICS/LABA) Combination

Symbidow capsule 400mcg / 12mcg formula

• Budesonide
• Formoterol Fumarate Dihydrate

Available forms

• Capsule for Inhalation

How to use Symbidow capsule 400mcg / 12mcg?

• Symbidow capsules are used only with the Dowhaler device, never swallowed like an ordinary capsule.
• The capsule is placed in the device chamber and pierced according to the device instructions before each use.
• The typical dose is one to two inhalations twice daily as prescribed for asthma, or as directed for COPD.
• Rinse the mouth with water and spit it out after each use to reduce the chance of oral thrush.
• Use this medicine regularly as a maintenance treatment, not only when symptoms flare.
• Keep a separate fast acting reliever inhaler on hand for sudden breathing difficulty.
• Review inhaler technique with a doctor or pharmacist periodically to confirm the correct dose is reaching the lungs.

Drug Interactions

• Ketoconazole and strong CYP3A4 inhibitors: These drugs can raise budesonide levels and increase the risk of steroid side effects.
• Beta blockers: These medicines can reduce the bronchodilator effect of formoterol.
• Other long acting beta agonists: Combining with similar inhalers is avoided to reduce the risk of excess stimulant effects.
• Diuretics: Formoterol can add to the potassium lowering effect of certain water pills.

Risks and warnings

• Oral thrush: The inhaled steroid can allow yeast infection in the mouth and throat if the mouth is not rinsed after use.
• Paradoxical bronchospasm: Rarely, wheezing can worsen immediately after use, requiring an alternate reliever and prompt medical review.
• Heart rhythm effects: The formoterol component can raise heart rate and, rarely, cause palpitations or arrhythmia.
• Growth monitoring in adolescents: Long term inhaled steroid use is monitored for effects on growth in younger patients.
• Not for acute attacks: This medicine is a maintenance treatment and is not used to relieve a sudden asthma attack.

Symbidow Capsule Side Effects

Local effects in the mouth and throat are the most frequently reported.

• Oral thrush
• Throat irritation
• Hoarse voice
• Headache
• Tremor
• Cough

Serious effects need urgent medical attention.

• Sudden worsening of wheezing or breathing difficulty after use
• Fast or irregular heartbeat

Storage Conditions

• Room temperature storage away from moisture keeps the capsules and device effective.
• The capsule is removed from its blister only immediately before use.
• The Dowhaler device is kept clean and dry between uses.
• Keep out of reach of children.